Results 161 to 170 of about 7,004,183 (346)

The renaissance of general relativity in context

, 2020
This contributed volume explores the renaissance of general relativity after World War II, when it transformed from a marginal theory into a cornerstone of modern physics.
Blum, A, Lalli, Roberto, Blum, Alexander, Renn, Jürgen, Lalli, R, Renn, J   +5 more
core   +1 more source

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

FEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer, Angelique Kragl, Katrin Ziems, Juliane Glaubitz, Sophie Grammbauer, Susanne Hildebrandt, Mladen V. Tzvetkov, Gabriele Jedlitschky   +7 more
wiley   +1 more source

Coordinates, observables and symmetry in relativity [PDF]

, 2007
We investigate the interplay and connections between symmetry properties of equations, the interpretation of coordinates, the construction of observables, and the existence of physical relativity principles in spacetime theories. Using the refined notion
Westman, Hans, Sonego, Sebastiano, Sebastiano Sonego, Hans Westman   +3 more
core  

Testing general relativity with gravitational-wave catalogs: The insidious nature of waveform systematics. [PDF]

iScience, 2021
Moore CJ, Finch E, Buscicchio R, Gerosa D.   +3 more
europepmc   +1 more source

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

FEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner, Hainan Zhu, Carol Christine Bosholm, Heuy‐Ching Wang, Tracy Criswell, Anthony Atala, Jian‐Xing Ma, Yuanyuan Zhang   +7 more
wiley   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

FEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young, Omar Arias‐Gaguancela, Fiona Gibson, Morgan Grainger, Jodie Score, Amit Nathubhai, Mauricio Cafiero, Lee Richard Machado   +7 more
wiley   +1 more source

General relativity: a concise introduction

, 2019
This is a short textbook on general relativity and gravitation aimed at readers with a broad range of interests in physics, from cosmology to high energy physics to condensed ...
Carlip, Steven
core   +1 more source

Gravitational waves from disks around spinning black holes: Simulations in full general relativity. [PDF]

Phys Rev D, 2021
Wessel E, Paschalidis V, Tsokaros A, Ruiz M, Shapiro SL.   +4 more
europepmc   +1 more source

Refinement of amino‐acid conformation vs. difference density maps in time‐resolved serial femtosecond crystallography data analysis

FEBS Open Bio, EarlyView.
The dFoCC pipeline starts with observed DED and resting‐state coordinates, which are then used to generate a library of triggered states. Correlation analysis of the calculated DED features of each candidate vs observed DED permits quantitative evaluation of candidate structural quality.
Meng Iao Fong, Yuhei Hosokawa, Lars Oliver Essen, Manuel Maestre‐Reyna   +3 more
wiley   +1 more source

General relativity: basics and beyond

, 2013
A Broad Perspective on the Theory of General Relativity and Its Observable Implications General Relativity: Basics and Beyond familiarizes students and beginning researchers with the basic features of the theory of general relativity as well as some of ...
Date, Ghanashyam
core