Results 171 to 180 of about 10,399,375 (306)

A Gaussian Process Framework for Testing General Relativity with Gravitational Waves

open access: yesThe Astrophysical Journal
Gravitational-wave astronomy provides a promising avenue for the discovery of new physics beyond general relativity as it probes extreme curvature and ultrarelativistic dynamics.
Lachlan Passenger   +5 more
doaj   +1 more source

Centennial of general relativity: a celebration

open access: yes, 2017
It has been over 100 years since the presentation of the Theory of General Relativity by Albert Einstein, in its final formulation, to the Royal Prussian Academy of Sciences.
Vasconcellos, César Augusto Zen
core  

Directed evolution of enzymes at the crossroads of tradition and innovation

open access: yesFEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova   +2 more
wiley   +1 more source

Discrete Approaches to Quantum Gravity in Four Dimensions

open access: yesLiving Reviews in Relativity, 1998
The construction of a consistent theory of quantum gravity is a problem in theoretical physics that has so far defied all attempts at resolution. One ansatz to try to obtain a non-trivial quantum theory proceeds via a discretization of space-time and the
Loll Renate
doaj  

Hyperactive ice‐binding proteins stabilize cell membranes and improve resistance to dehydration stress in Caenorhabditis elegans

open access: yesFEBS Open Bio, EarlyView.
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose   +9 more
wiley   +1 more source

The Thermodynamics of Black Holes

open access: yesLiving Reviews in Relativity, 2001
We review the present status of black hole thermodynamics. Our review includes discussion of classical black hole thermodynamics, Hawking radiation from black holes, the generalized second law, and the issue of entropy bounds.
Wald Robert M.
doaj  

Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA

open access: yesFEBS Open Bio, EarlyView.
PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro   +1 more
wiley   +1 more source

Horizon phase spaces in general relativity

open access: yesJournal of High Energy Physics
We derive a prescription for the phase space of general relativity on two intersecting null surfaces using the null initial value formulation. The phase space allows generic smooth initial data, and the corresponding boundary symmetry group is the ...
Venkatesa Chandrasekaran   +1 more
doaj   +1 more source

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

open access: yesFEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya   +2 more
wiley   +1 more source

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