Results 141 to 150 of about 15,159,360 (304)

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

open access: yesMolecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park   +6 more
wiley   +1 more source

Lobbying expenditures (Ohio. General Assembly. Office of the Legislative Inspector General); Other title: Title from Lobbying statistics home page: Lobbying statistics reports. Annual reports

open access: yes, 2005
2004-2005.; Harvested from the web on 6/26/14Presents total expenditures; an analysis of the total expenditures by type of lobbying and by source of expenditure; an analysis of annual expenditures over $10,000 by source; and, lobbying registration ...

core   +1 more source

General solutions of weakly delayed discrete systems in 3D

open access: yesAdvances in Nonlinear Analysis
Discrete systems x(k+1)=Ax(k)+Bx(k−m)x\left(k+1)=Ax\left(k)+Bx\left(k-m), k=0,1,…k=0,1,\ldots \hspace{0.33em} are analyzed, where mm is a fixed positive integer, AA, BB are constant 3 by 3 matrices and x:{−m,−m+1,…}→R3x:\left\{-m,-m+1,\ldots \right\}\to {
Diblík Josef   +3 more
doaj   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

open access: yesMolecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang   +9 more
wiley   +1 more source

Translating whole‐genome doubling into precision medicine in cancer

open access: yesMolecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

Method of states on the basis of Kilchevskiy's equations for analysis of 3d steady-state oscillation

open access: yesVestnik Samarskogo Gosudarstvennogo Tehničeskogo Universiteta. Seriâ: Fiziko-Matematičeskie Nauki, 2011
General solution of N. A. Kilchevskiy's equations for oscillating three-dimensional solids is constructed. Method of states for analysis of boundary-value problem about oscillations is proven, it is based on the following terms: states of medium ...
Victor B Pen'kov, Ivan N Stebenev
doaj  

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

open access: yesMolecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

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