Results 141 to 150 of about 1,814,913 (312)
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
, 1995 The guardians of children brought to the Port Moresby General Hospital's Children's Outpatient Department with a chief complaint of diarrhoeal disease were questioned regarding their preference of glucose-based vs rice-based oral rehydration solution ...
Todaro, W. +3 more
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On a general solution of Hill's equation [PDF]
, 1918 i. ON A GENERAL SOLUTION OF HILL'S EQUATION. BY E. LINDSAY INCE. Reprinted from the MONTHLY NOTICES OF THE ROYAL ASTRONOMICAL SOCIETY, Vol. LXIV. No. 5. • ii. NOTES ON THE GENERAL SOLUTION OF HILL'S EQUATION. BY E. LINDSAY INCE.
Ince, E. Lindsay
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Geometric general solution to the U(1) anomaly equations
, 2020 : Costa et al. [Phys. Rev. Lett.123 (2019) 151601] recently gave a general solution to the anomaly equations for n charges in a U(1) gauge theory.
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Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
A System of Four Generalized Sylvester Matrix Equations over the Quaternion Algebra
MathematicsIn this paper, we make use of the simultaneous decomposition of eight quaternion matrices to study the solvability conditions and general solutions to a system of two-sided coupled Sylvester-type quaternion matrix equations AiXiCi+BiXi+1Di=Ωi,i=1,2,3,4 ...
Zhuo-Heng He, Jie Tian, Shao-Wen Yu
doaj +1 more source
Molecular Oncology, EarlyView.Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute +4 more
wiley +1 more source
On the Dynamics of Some Higher-Order Nonlinear Difference Equations
MathematicsThis research investigates the dynamics of higher-order nonlinear difference equations, specifically concentrating on seventh-order instances. Analytical solutions are obtained for particular equations, a formidable task owing to the absence of explicit ...
Turki D. Alharbi, Md Rifat Hasan
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CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
Molecular Oncology, EarlyView.PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
Molecular Oncology, EarlyView.Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source