Results 81 to 90 of about 179,210 (301)

Targeted H2S Delivery System Attenuates Blood‐Spinal Cord Barrier Disruption after Spinal Cord Injury by Reshaping the Ferritinophagy Pathway

Advanced Science, EarlyView.
The αvβ3‐mediated SPRC@MPDA‐RGD targets broken endothelial cells and controlled‐ releases SPRCcontrollably releases SPRC. CSE is then activated to produce endogenous H2S, which inhibits ferritinophagy. In brief, H2S inhibits autophagy by activating the PI3K/Akt/mTOR pathway, thereby suppressing the ferroptosis process mediated by NCOA4, and ultimately ...
Zhiheng Chen, Xinkai Pu, Ruiyang Li, Yuezhou Wu, Qirong Zhou, Jian Wang, Yuxuan Qian, Fengjie Lu, Jian‐Yuan Zhao, Zhida Su, Jiacan Su, Xiaofeng Lian   +11 more
wiley   +1 more source

Conservative management for postprostatectomy urinary incontinence [PDF]

, 2015
BACKGROUND: Urinary incontinence is common after radical prostatectomy and can also occur in some circumstances after transurethral resection of the prostate (TURP).
Abbinante, Aboseif, Abrams, Ahmed, Albertsen, Altman, Bales, Berghmans, Berghmans, Bocker, Burgio, Burgio, Burkert, Burnett, Campbell, Centemero, Centemero, Chang, Chao, Cornel, Cornu, Crevenna, Crivellaro, Crivellaro, Delmastro, Dieperink, Dijkstra-Eshuis, Donnellan, Dorey, Dorey, Dubbelman, Dubbelman, Dubbelman, Dubbelman, Eastham, Eren, Eren, Fader, Fader, Fader, Ficazzola, Filocamo, Filocamo, Foratos, Franke, Franke, Galloway, Geraerts, Glazener, Glazener, Glazener, Glazener, Glazener, Glazener, Golubuff, Goode, Goode, Grise, Groutz, Gudziak, Guyatt, Guyatt, Guyatt, Guyatt, Hagen, Hagen, Higgins, Hoffmann, Hotston, Hou, Hunter, Hunter, Ip, Jabs, Jacobsen, Jahn, Joseph, Juni, Kahihara, Kampen, Kampen, Kampen, Khan, Kim, Koo, Laurienzo, Leach, Lilli, Lin, Liu, MacDonald, Majoros, Manassero, Marchiori, Mariotti, Martini, Mathewson-Chapman, Mathewson-Chapman, McCammon, McGlynn, McGuire, Milsom, Mishel, Moore, Moore, Moore, Moore, Moore, Moore, Moore, Moore, Morihiro, Morkved, Niël-Weise, Nowak, Omar, Opsomer, Ottenbacher, Overgard, Parekh, Park, Park, Pemberton, Peyromaure, Popolo, Porru, Prota, Rainwater, Rassweiler, Ribeiro, Ribeiro, Ribiero, Ricci, Robinson, Robinson, Robinson, Sacco, Sacco, Salinas Casado, Salinas Casado, Sciarra, Sciarra, Shen, Silva, Simeit, Sueppel, Thompson, Tibaek, Tibaek, Tienforti, Tobia, Traeger, Turner, Uebersax, Update Buckley, Update Buckley, Update Glazener, Update Glazener, Update Nilssen, Voorham-Van Der Zalm, Ware, Wille, Wille, Wilson, Winters, Yamanishi, Yamanishi, Yang, Yao, Yokoyama, Zahariou, Zellner, Zermann, Zhang, Zhang, Zhang, Zhang, Zopf   +177 more
core   +1 more source

Endothelial PDGF Signaling Dysregulation Impairs Testicular Interstitial Homeostasis in Diabetes

Advanced Science, EarlyView.
Testicular endothelial cells (TECs) function as central signaling hubs that coordinate interstitial homeostasis. Diabetes disrupts TEC‐derived PDGF signaling, silences the JUND‐MCL1 survival program in Leydig cells, and impairs peritubular function, leading to fibrosis and testosterone insufficiency.
Wenxiu Zhang, Kai Hong, Yanling Tang, Lina Cui, Xiaojian Lu, Jianxing Cheng, Yangyi Fang, Qiaoling Jiang, Ziyan Zhuang, Songzhan Gao, Hui Jiang, Qiang Liu, Jingtao Guo, Zhe Zhang, Xiaoyan Wang   +14 more
wiley   +1 more source

Asymmetric Cu─N─Ru Bridgedsite Nanozyme‐Loaded Injectable Thermogel Boosts Cuproptosis‐Like Death for Multidrug‐Resistant Urinary Tract Infections

Advanced Science, EarlyView.
To address multidrug‐resistant urinary tract infections (MDR‐UTIs), we developed Cu‐ZIF8‐Ru nanozyme featuring an asymmetric Cu─N─Ru catalytic site. This unique structure enhances multienzyme‐mimetic activity, eradicating resistant bacteria by inducing a cuproptosis‐like death pathway through intracellular Cu2+ accumulation and energy depletion.
Guanlin Li, Shike Zhang, Jinggong Liu, Xin Wang, Heng Wang, Hongcan Yang, Yuhao Zhou, Wen Liu, Hongxing Liu, Wenqi Wu   +9 more
wiley   +1 more source

Predictors of pelvic pain in a general urology clinic population. [PDF]

BJUI Compass, 2023
Prillaman G, Zillioux J, Beller H, Yeaman C, Rapp D.   +4 more
europepmc   +1 more source

Phosphatidic Acid‐TRIM59‐Olig2 Signaling Couples Metabolic Dysfunction to Myelination Failure in PWMI

Advanced Science, EarlyView.
PA accumulates after hypoxic‐ischemic injury and stabilizes the E3 ligase TRIM59 in OPCs. Stabilized TRIM59 enhances ubiquitination and degradation of Olig2, blocking differentiation and causing hypomyelination in PWMI. Modulating PA synthesis restores Olig2 levels, improves myelination, and ameliorates behavioral deficits, defining a metabolically ...
Xinyu Li, Yanan Liu, Meng Zhang, Yiwei Liu, Meiting Liu, Kaishen Zhu, Zhian Liu, Chao Ren, Ruiqin Yao   +8 more
wiley   +1 more source

Progress [PDF]

, 1989
Magazine reporting on the activities and programs of the University Hospital at Boston University Medical ...
Office of Publication Services, Boston University Medical Center
core  

Accuracy of multiparametric magnetic resonance imaging for diagnosing prostate Cancer: a systematic review and meta-analysis

BMC Cancer, 2019
Background The application of multiparametric magnetic resonance imaging (mpMRI) for diagnosis of prostate cancer has been recommended by the European Association of Urology (EAU), National Comprehensive Cancer Network (NCCN), and European Society of ...
Liang Zhen, Xiaoqiang Liu, Chen Yegang, Yang Yongjiao, Xu Yawei, Kang Jiaqi, Wang Xianhao, Song Yuxuan, Hu Rui, Zhang Wei, Ou Ningjing   +10 more
doaj   +1 more source

Managing advanced prostate cancer: No longer the primary domain of general urology. [PDF]

Can Urol Assoc J, 2022
Aprikian A.
europepmc   +1 more source

Aptamer‐Engineered Liposomal Platform Enables in Situ cDC1 Vaccination to Potentiate Immunotherapy in Prostate Cancer

Advanced Science, EarlyView.
Prostate cancer is immunologically ‘cold’, with scarce, dysfunctional type 1 conventional dendritic cells (cDC1s) that limit T cell priming. We introduce an aptamer‐targeted liposomedelivering FMS‐like tyrosine kinase 3 ligand (Flt3L) and chlorin e6 (Ce6). Ultrasound induces antigen release and cDC1s recruitment, creating an in situ cDC1 vaccine.
Jiayi Wang, Xuan Wang, Xinfeng Dai, Linxin Tian, Wencheng Shen, Xueliang Liu, Wei Xue, Jiahua Pan, Yu Yang   +8 more
wiley   +1 more source