Results 101 to 110 of about 6,965 (284)
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas +3 more
wiley +1 more source
The Problem of Conspiracism [PDF]
Belief in conspiracy theories is typically considered irrational, and as a consequence of this, conspiracy theorists––those who dare believe some conspiracy theory––have been charged with a variety of epistemic or psychological failings.
Dentith, Matthew R. X.
core
Aggressive prostate cancer is associated with pericyte dysfunction
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero +11 more
wiley +1 more source
Effect of habitat degradation on competition, carrying capacity, and species assemblage stability [PDF]
In human-impacted rivers, nutrient pollution has the potential to disrupt biodiversity organisation and ecosystem functioning, prompting calls for effective monitoring and management.
Calizza, Edoardo +3 more
core +1 more source
Bed bugs: The move to humans as hosts
Cimicid insects, bed bugs and their allies, include about 100 species of blood-feeding ectoparasites. Among them, a few have become widespread and abundant pests of humans. Cimicids vary in their degree of specialization to hosts.
Benoit Talbot +2 more
doaj +1 more source
Immunosuppressive drugs for solid organ transplantation are critical dose drugs with a narrow therapeutic index. Many of the most commonly used innovator drugs are off patent and have been replicated by generic counterparts, often at substantial cost-savings to the patient.
Mara Medeiros +4 more
openaire +5 more sources
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié +13 more
wiley +1 more source
Scientific explanation and moral explanation [PDF]
Moral philosophers are, among other things, in the business of constructing moral theories. And moral theories are, among other things, supposed to explain moral phenomena.
Leibowitz, Uri D.
core +1 more source
Next‐generation proteomics improves lung cancer risk prediction
This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj +4 more
wiley +1 more source
The Ghost of Patrick Geddes: Civics As Applied Sociology [PDF]
In 1904 and 1905 Patrick Geddes (1905, 1906) read his famed, but today little-read, two-part paper, \'Civics: as Applied Sociology\', to the first meetings of the British Sociological Society.
Alex Law
core

