Results 101 to 110 of about 962,972 (291)

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner   +14 more
wiley   +1 more source

Systematic Observation: Relevance of This Approach in Preschool Executive Function Assessment and Association with Later Academic Skills

open access: yesFrontiers in Psychology, 2017
Executive functions (EFs) are high-level cognitive processes that allow us to coordinate our actions, thoughts, and emotions, enabling us to perform complex tasks.
Elena Escolano-Pérez   +3 more
doaj   +1 more source

Methodische Grundlagen und Anwendungen der Generalisierbarkeitstheorie in der betriebswirtschaftlichen Forschung [PDF]

open access: yes
Generalizability theory provides an alternative and more flexible approach for construct measurement than classical measurement theory. The theory takes into account several sources of error.
Eisend, Martin
core  

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

open access: yesMolecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak   +10 more
wiley   +1 more source

A General Algorithm for Deciding Transportability of Experimental Results

open access: yesJournal of Causal Inference, 2013
Generalizing empirical findings to new environments, settings, or populations is essential in most scientific explorations. This article treats a particular problem of generalizability, called “transportability”, defined as a license to transfer ...
Bareinboim Elias, Pearl Judea
doaj   +1 more source

Main and Regional Campus Assessments of Applicants to a Rural Physician Leadership Program

open access: yesJournal of Regional Medical Campuses, 2019
While the selection of qualified applicants often relies, in part, on scores generated from a medical school pre-admission interview (MSPI), the growth of regional medical campuses (RMCs) – many with specialized rural tracks, programs, or missions – has ...
Terry Stratton   +2 more
doaj   +1 more source

Measuring interaction: An empirical comparison of three OLS regression models [PDF]

open access: yes, 2008
The capacity to correctly assess the existence of interaction is a high-value modeling capability among researchers of information systems (IS), especially those focusing on behavioural paradigm studies.
Saleh Zolait, AZ   +2 more
core  

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

open access: yesFEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

A Study on Replay Attack and Anti-Spoofing for Automatic Speaker Verification

open access: yes, 2017
For practical automatic speaker verification (ASV) systems, replay attack poses a true risk. By replaying a pre-recorded speech signal of the genuine speaker, ASV systems tend to be easily fooled.
Chen, Yixiang   +3 more
core   +1 more source

Differential regulation of ZFAS1 splice variants by endoplasmic reticulum stress in hepatocyte cell lines

open access: yesFEBS Open Bio, EarlyView.
ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand   +2 more
wiley   +1 more source

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