Results 91 to 100 of about 962,972 (291)
Estimating preclinical amyloid positivity: A case study transporting ADNI to ARIC
Alzheimer’s & Dementia: Translational Research & Clinical InterventionsINTRODUCTION Alzheimer's disease and related dementias researchers have benefited from deeply phenotyped clinical samples; however, there is a critical need for estimates that generalize to diverse, representative populations.
Emma K. Stapp +10 more
doaj +1 more source
Uncovering the genetic architecture and evolutionary roots of androgenetic alopecia in African men
HGG AdvancesSummary: Androgenetic alopecia is a highly heritable trait. However, much of our understanding about the genetics of male-pattern baldness comes from individuals of European descent.
Rohini Janivara +23 more
doaj +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
RESIdual STability (RESIST) Calibration for Improved Hydrological Model Time Generalizability
Water Resources ResearchHydrological models are calibrated on specific periods based on how well simulations match streamflow observations by selecting the parameter vector(s) that provide the highest accuracy.
Paul C. Astagneau +4 more
doaj +1 more source
Generalizability of High Frequency Oscillation Evaluations in the Ripple Band
Frontiers in Neurology, 2018 Objective: We examined the interrater reliability and generalizability of high-frequency oscillation (HFO) visual evaluations in the ripple (80–250 Hz) band, and established a framework for the transition of HFO analysis to routine clinical care. We were
Aaron M. Spring +14 more
doaj +1 more source
Sources of Measurement Error in an ECG Examination: Implications for Performance-Based Assessments [PDF]
, 2003 Objective: To assess the sources of measurement error in an electrocardiogram (ECG) interpretation examination given in a third-year internal medicine clerkship. Design: Three successive generalizability studies were conducted.
Ferenchick MD, Gary +1 more
core
Molecular Oncology, EarlyView.Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau +8 more
wiley +1 more source
The case for multiple UESDs and an application to migrant deaths in the Mediterranean Sea
Political Science Research and MethodsMany recent applications of the “Unexpected Event during Survey Design” (UESD) analyze single cases of frequently occurring events. In this research note, I question the generalizability of research findings obtained this way and demonstrate the ...
Joris Frese
doaj +1 more source
Development of the Motivational Interviewing Supervision and Training Scale [PDF]
, 2005 The movement to use empirically supported treatments has increased the need for researchers and supervisors to evaluate therapists’ adherence to and the quality with which they implement those interventions. Few empirically supported approaches exist for
Barrett, David E. +4 more
core +1 more source
Modeling Camera Effects to Improve Visual Learning from Synthetic Data
, 2018 Recent work has focused on generating synthetic imagery to increase the size and variability of training data for learning visual tasks in urban scenes.
A Andreopoulos +10 more
core +1 more source