Results 91 to 100 of about 488,215 (260)
FEBS Letters, EarlyView.This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
Generalizations of Morphic Group Rings
International Journal of Mathematics and Mathematical Sciences, 2007 An element a in a ring R is called left morphic if there exists b∈R such that 1R(a)=Rb and 1R(b)=Ra. R is called left morphic if every element of R is left morphic.
Libo Zan, Jianlong Chen, Qinghe Huang
doaj +1 more source
Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer
FEBS Letters, EarlyView.Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani +4 more
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Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
FEBS Letters, EarlyView.Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
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On theorems of R. Rado and of D. Watson
Моделирование и анализ информационных систем, 2007 Theorems of R. Rado and of D. Watson are generalizations for theorems P. Kirchberger and C. Caratheodory. In the paper we will consider some generalizations and refinements for these theorems .
V. L. Dol'nikov
doaj
Generalized multidimensional Hilbert transforms in Clifford analysis
International Journal of Mathematics and Mathematical Sciences, 2006 Two specific generalizations of the multidimensional Hilbert transform in Clifford analysis are constructed. It is shown that though in each of these generalizations some traditional properties of the Hilbert transform are inevitably lost, new bounded ...
Fred Brackx +2 more
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The role of histone modifications in transcription regulation upon DNA damage
FEBS Letters, EarlyView.This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
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Refinements and Generalizations of Functional Dresher’s and Bellman’s Inequalities
Abstract and Applied Analysis, 2015 We give refinements and generalizations of the Dresher and Bellman inequalities for positive linear functionals. We also give reverse of the new obtained generalized version of these inequalities.
Rabia Bibi, Muhammad Shahzad
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Two generalizations of Jacobi's derivative formula
, 2005 In this paper we generalize the famous Jacobi's triple product identity, considered as an identity for theta functions with characteristics and their derivatives, to higher genus/dimension.
Grushevsky, Samuel +1 more
core
FEBS Letters, EarlyView.Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
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