Results 81 to 90 of about 488,215 (260)
FEBS Letters, EarlyView.Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
The Generalizations of Hilbert's Inequality
International Journal of Mathematics and Mathematical Sciences, 2008 By introducing some parameters and estimating the weight functions, we establish a new Hilbert-type inequalities with best constant factors. The equivalent inequalities are also considered.
Liubin Hua, Huazhong Ke, Yongjin Li
doaj +1 more source
Completions of Kleene's second model [PDF]
Logical Methods in Computer ScienceWe investigate completions of partial combinatory algebras (pcas), in particular of Kleene's second model $\mathcal{K}_2$ and generalizations thereof. We consider weak and strong notions of embeddability and completion that have been studied before in ...
Sebastiaan A. Terwijn
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Pediatric Nephrology, 2017 Immunosuppressive drugs for solid organ transplantation are critical dose drugs with a narrow therapeutic index. Many of the most commonly used innovator drugs are off patent and have been replicated by generic counterparts, often at substantial cost-savings to the patient.
Mara Medeiros +4 more
openaire +5 more sources
By dawn or dusk—how circadian timing rewrites bacterial infection outcomes
FEBS Letters, EarlyView.The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo +2 more
wiley +1 more source
Some elementary observations regarding reductive Cartan geometries
, 2016 After defining generalizations of the notions of covariant derivatives and geodesics from Riemannian geometry for reductive Cartan geometries in general, various results for reductive Cartan geometries analogous to important elementary results from ...
Erickson, Jacob W.
core
The role and implications of mammalian cellular circadian entrainment
FEBS Letters, EarlyView.At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley +1 more source
Scientific AfricanIn this paper, we provide novel generalizations of the D-type-I functions by relaxing the D-Preinvexity functions using the mean-valued theorem. Under these new generalizations of the D-Preinvexity type-I functions, we also study the optimality solutions
Mohamed Abd El-Hady Kassem +1 more
doaj +1 more source
Peptide‐based ligand antagonists block a Vibrio cholerae adhesin
FEBS Letters, EarlyView.The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang +9 more
wiley +1 more source
New Conformally Invariant Born–Infeld Models and Geometrical Currents
PhysicsA new conformally invariant gravitational generalization of the Born–Infeld (BI) model is proposed and analyzed from the point of view of symmetries. Taking a geometric identity involving the determinant functions detfBμν, Fμν with the Bach Bμν and the ...
Diego Julio Cirilo-Lombardo
doaj +1 more source