Results 71 to 80 of about 60,902 (256)

Forecasting the Dialysis Burden in Japan: Validation‐Based Projections of Prevalence and Incidence Through 2050

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Japan has one of the highest dialysis prevalence rates worldwide and a shrinking, aging population. Whether dialysis burden has entered a sustained post‐peak phase or whether recent declines partly reflect pandemic‐related disruptions remains uncertain.
Hatice Şahin, Berrak Itır Aylı, Nüket Paksoy   +2 more
wiley   +1 more source

Association Between Individualized Education for Kidney Replacement Therapy Modality Selection and Peritoneal Dialysis Initiation: A Cross‐Sectional Study

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Peritoneal dialysis (PD) is an established home‐based kidney replacement therapy (KRT), but its uptake remains low in Japan. We evaluated whether individualized education in a dedicated outpatient clinic was associated with the initiation of PD.
Yasuko Ito, Ryuichi Yoshimura, Takaki Yamauchi, Yuta Funakoshi, Hirotaka Sonoda, Seiji Kobayashi, Hiroyuki Terawaki, Takafumi Ito   +7 more
wiley   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Curved Text Line Rectification via Bresenham’s Algorithm and Generalized Additive Models

Signals
This paper presents a methodology for rectifying curved text lines, a crucial process in optical character recognition (OCR) and computer vision. Utilizing generalized additive models (GAMs), the proposed method accurately estimates text curvature and ...
Thomas Stogiannopoulos, Ilias Theodorakopoulos   +1 more
doaj   +1 more source

Generalized Additive Modelling of Sample Extremes

Journal of the Royal Statistical Society Series C: Applied Statistics, 2004
SummaryWe describe smooth non-stationary generalized additive modelling for sample extremes, in which spline smoothers are incorporated into models for exceedances over high thresholds. Fitting is by maximum penalized likelihood estimation, with uncertainty assessed by using differences of deviances and bootstrap simulation. The approach is illustrated
Chavez-Demoulin, V., Davison, A. C.
openaire   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Generalized Additive Models

Annual Review of Statistics and Its Application
Generalized additive models are generalized linear models in which the linear predictor includes a sum of smooth functions of covariates, where the shape of the functions is to be estimated. They have also been generalized beyond the original generalized linear model setting to distributions outside the exponential family and to situations in which ...
openaire   +2 more sources

Application of generalized additive models to explore minerals in sheep milk

Journal of Dairy Science
: This study explores the complex relationships among ovine milk minerals (Ca, P, Na, K, Mg, K, Cl, respectively) and different factors employing generalized additive mixed models (GAMM). The GAMM included milk yield (MY), parity, and breed as parametric
Stefano Biffani, Michela Ablondi, Claudio Cipolat-Gotet, Andrea Summer, Elena Mariani, Johanna Ramírez-Díaz, Alessio Negro, Alessandro Lotto, Giorgia Stocco   +8 more
doaj   +1 more source

Generalized functional additive mixed models

Electronic Journal of Statistics, 2016
We propose a comprehensive framework for additive regression models for non-Gaussian functional responses, allowing for multiple (partially) nested or crossed functional random effects with flexible correlation structures for, e.g., spatial, temporal, or longitudinal functional data as well as linear and nonlinear effects of functional and scalar ...
Scheipl, Fabian, Gertheiss, Jan, Greven, Sonja   +2 more
openaire   +4 more sources