Results 81 to 90 of about 60,902 (256)

The human gut microbiome across the life course

open access: yesFEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero   +4 more
wiley   +1 more source

A comparative analysis of generalized additive models for obesity risk prediction

open access: yesHealthcare Analytics
Obesity is a growing global health crisis, and traditional regression models often fail to capture the complex relationships between risk factors, limiting predictive accuracy and hindering effective public health interventions.
Olushina Olawale Awe   +4 more
doaj   +1 more source

Modeling Linguistic Variables With Regression Models: Addressing Non-Gaussian Distributions, Non-independent Observations, and Non-linear Predictors With Random Effects and Generalized Additive Models for Location, Scale, and Shape

open access: yesFrontiers in Psychology, 2018
As statistical approaches are getting increasingly used in linguistics, attention must be paid to the choice of methods and algorithms used. This is especially true since they require assumptions to be satisfied to provide valid results, and because ...
Christophe Coupé
doaj   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Predicting motor insurance claim incidence using generalized and tree-based models: A comparative statistical approach [PDF]

open access: yesInsurance Markets and Companies
Type of the article: Research Article AbstractAccurate prediction of motor insurance claim frequency is necessary for efficient risk management, underwriting, and policy pricing.
Eslam Abdelhakim Seyam
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Generalized Additive Models for Location Scale and Shape (GAMLSS) in R

open access: yesJournal of Statistical Software, 2007
GAMLSS is a general framework for fitting regression type models where the distribution of the response variable does not have to belong to the exponential family and includes highly skew and kurtotic continuous and discrete distribution.
D. Mikis Stasinopoulos, Robert A. Rigby
doaj  

Incorporating shape constraints in generalized additive modelling of the height-diameter relationship for Norway spruce

open access: yesForest Ecosystems, 2016
Background: Measurements of tree heights and diameters are essential in forest assessment and modelling. Tree heights are used for estimating timber volume, site index and other important variables related to forest growth and yield, succession and ...
Natalya Pya, Matthias Schmidt
doaj   +1 more source

A General Framework for Prediction in Generalized Additive Models

open access: yes, 2020
Smoothing techniques have become one of the most popular modelling approaches in the unidimensional and multidimensional setting. However, out-of-sample prediction in the context of smoothing models is still an open problem that can significantly widen the use of these models in many areas of knowledge.
openaire   +3 more sources

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

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