Results 51 to 60 of about 961,498 (296)

Finite difference and averaging operators in generalized entropies

, 2010
In the two-parameter generalization of thermostatistics based on the Sharma-Taneja-Mittal entropy not only the generalized entropic functional Sa,b but also a new functional Script Ia,b plays a fundamental role.
T Wada, AM Scarfone
core   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

Generalized Cubic Aggregation Operators with Application in Decision Making Problem

Journal of New Theory, 2018
There are many aggregation operators and their applications have been developed up to date, but in this paper we introduced the idea of generalized aggregation operator.
Muhammad Shakeel, Saleem Abdullah, Aliya Fahmi   +2 more
doaj  

Comparison of accuracy in ranking alternatives performing generalized fuzzy average functions

Technological and Economic Development of Economy, 2013
The paper defines the notions of point, interval and triangular intuitionistic fuzzy numbers expressing the degree of membership and non-membership in the fuzzy set.
Natalja Kosareva, Aleksandras Krylovas
doaj   +1 more source

Cross Subaperture Averaging Generalized Sidelobe Canceler Beamforming Applied to Medical Ultrasound Imaging

Applied Sciences, 2021
For adaptive ultrasound imaging, a reliable estimation of the covariance matrix has a decisive influence on the performance of beamformers. In this paper, we propose a new cross subaperture averaging generalized sidelobe canceler approach (GSC-CROSS) for
Jin Yang, Jiake Li, Xiaodong Chen, Jiaqi Xi, Huaiyu Cai, Yi Wang   +5 more
doaj   +1 more source

Smaller is better: nanobodies meet NMR

FEBS Letters, EarlyView.
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

A Generalized Data-Weighted Averaging Algorithm

IEEE Transactions on Circuits and Systems II: Express Briefs, 2010
This brief presents a definition to a general data-weighted averaging algorithm that realizes D/A converter (DAC) mismatch shaping transfer function of the form 1 ± z - D. The mathematical background of the transfer function leads to an intuitive algorithm realized as a simple fixed-point simulation model that converges into a hardware-efficient ...
Neitola Marko, Rahkonen Timo
openaire   +1 more source

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

Molecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche, Niels J. van Ruitenbeek, Charlotte Adang, Luke O'Gorman, Pui Yuen Lee, Willemijn M. Klein, Adriana C. H. van Engen‐van Grunsven, Jack A. Schalken, Sander Bervoets, Gerald W. Verhaegh, Carla M. L. van Herpen   +10 more
wiley   +1 more source

Characterization of therapeutic antibodies targeting lymphatic and vascular resistance factor for the treatment of hypervascularized and highly metastatic cancers

Molecular Oncology, EarlyView.
LVRF (lymphatic and vascular resistance factor) is a VEGFA splice variant upregulated in response to anti‐angiogenic therapy that fosters tumor adaptation through enhanced vascularization, lymphangiogenesis, and metastatic dissemination. Targeting LVRF with fully human neutralizing antibodies disrupts these processes and limits resistant tumor growth ...
Marion David, Arthur Karaulic, Audrey Bennetot, Clémence Fournier, Quentin Odet, Arthur Gouraud, Isabelle Bourget, Cédric Gaggioli, Sandy Giuliano, Frédéric Luciano, Olivier Léger, Zaki Sellam, Gilles Pagès   +12 more
wiley   +1 more source