Results 101 to 110 of about 55,433 (287)

Discovery and Targeted Proteomic Studies Reveal Striatal Markers Validated for Huntington's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Clinical trials for Huntington's disease (HD) enrolling persons before clinical motor diagnosis (CMD) lack validated biomarkers. This study aimed to conduct an unbiased discovery analysis and a targeted examination of proteomic biomarkers scrutinized by clinical validation. Methods Cerebrospinal fluid was obtained from PREDICT‐HD and
Daniel Chelsky, Cara Joyce, H. Jeremy Bockholt, Paul A. Rudnick, William H. Adams, Fiona McAllister, Justin W. Smock, Michael A. Newton, Jane S. Paulsen   +8 more
wiley   +1 more source

Epilepsia partialis continua in mitochondrial dysfunction: Interesting phenotypic and MRI observations

Annals of Indian Academy of Neurology, 2008
An 11-year-old girl manifested with photophobia, ptosis, external ophthalmoplegia, hypotonia, weakness of proximal limb muscles, hyporeflexia, and generalized seizures (six months).
Karkare Kalyani, Sinha Sanjib, Ravishankar Shivashankar, Gayathri Narayanappa, Yasha T, Goyal Manoj, Vijayan Joy, Vanniarajan Ayyasamy, Thangaraj Kumarswamy, Taly Arun   +9 more
doaj  

Embedding 1D Euler Beam in 2D Classical Continua

Fibers
In this contribution, the classical Cauchy first-gradient elastic theory is used to solve the equilibrium problem of a bidimensional (2D) reinforced elastic structure under small displacements and strains.
Armine Ulukhanyan, Luca Placidi, Anil Misra, Roberto Fedele, Raimondo Luciano, Francesco Fabbrocino   +5 more
doaj   +1 more source

Generalized continua with applications

Continuum Mechanics and Thermodynamics, 2022
Altenbach H., Eremeyev V. A.
openaire   +1 more source

Predicting Epileptogenic Tubers in Patients With Tuberous Sclerosis Complex Using a Fusion Model Integrating Lesion Network Mapping and Machine Learning

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Accurate localization of epileptogenic tubers (ETs) in patients with tuberous sclerosis complex (TSC) is essential but challenging, as these tubers lack distinct pathological or genetic markers to differentiate them from other cortical tubers.
Tinghong Liu, Qi Wang, Suhui Kuang, Dezhi Cao, Ping Ding, Shaohui Zhang, Haihua Wei, Zhirong Wei, Jinshan Xu, Xinyu Huang, Bing Liu, Shuli Liang   +11 more
wiley   +1 more source

Generalized Cantor manifolds and indecomposable continua

, 2012
We review results concerning homogeneous compacta and discuss some open questions. It is established that indecomposable continua are Alexandroff (resp., Mazurkiewicz, or strong Cantor) manifolds with respect to the class of all continua. We also provide some new proofs of Bing's theorems about separating metric compacta by hereditarily indecomposable ...
Todorov, V., Valov, V.
openaire   +2 more sources

Prognostic Implications of Sleep Architecture for Patients Admitted to the Intensive Care Unit With Status Epilepticus

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Status epilepticus (SE) is associated with significant mortality. Sleep architecture may reflect normal brain function. Impaired sleep architecture is associated with poorer outcomes in numerous conditions. Here we investigate the association of sleep architecture in continuous EEG (cEEG) with survival in SE.
Ran R. Liu, Marcus C. Ng, Gavin P. Winston, Sabrina Schaly, Garima Shukla, Lysa Boissé Lomax   +5 more
wiley   +1 more source

In‐Depth Profiling Highlights the Effect of Efgartigimod on Peripheral Innate and Adaptive Immune Cells in Myasthenia Gravis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Myasthenia gravis (MG) is an autoimmune disorder characterized by antibody‐mediated complement activation. Efgartigimod, a neonatal Fc receptor (FcRn) antagonist, is approved for treating generalized MG (gMG). However, its modulatory effects on upstream innate and adaptive immune cells remain largely unexplored.
Lei Jin, Liu Dong, Ying Wang, Dingxian He, Chong Yan, Jianying Xi, Haoqin Jiang, Yu Shi, Ming Guan, Chongbo Zhao, Jie Song, Sushan Luo   +11 more
wiley   +1 more source

Super‐Refractory Status Epilepticus (SRSE) in a Patient With Compound Heterozygous OPA1 Variants: Case Report and Literature Review

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Super‐Refractory Status Epilepticus (SRSE) is a rare, life‐threatening neurological emergency with unclear etiology in many cases. Mitochondrial dysfunction, often due to disease‐causing genetic variants, is increasingly recognized as a cause, with each gene producing distinct pathophysiological mechanisms.
Pouria Mohammadi, Lara Basovic, Christopher Michael McGraw   +2 more
wiley   +1 more source

On the Weyl Transform with Symbol in the Gel'fand-Shilov Space and its Dual Space

Cubo, 2010
In this paper, we claim two subjects. One is that the Weyl transform with symbol in the Gel'fand-Shilov space l r r , r ≥ 1/2 , is a trace class operator.
YASUYUKI OKA
doaj