Results 71 to 80 of about 55,433 (287)

Applicability of mitotic figure counting by deep learning: a development and pan‐cancer validation study

open access: yesFEBS Open Bio, EarlyView.
In this study, we developed a deep learning method for mitotic figure counting in H&E‐stained whole‐slide images and evaluated its prognostic impact in 13 external validation cohorts from seven different cancer types. Patients with more mitotic figures per mm2 had significantly worse patient outcome in all the studied cancer types except colorectal ...
Joakim Kalsnes   +32 more
wiley   +1 more source

Two-level system with noise: Blue's function approach

open access: yes, 1997
By using the random matrix approach and generalized Blue's function representation we solve analytically the model of an effective two-level system coupled to a noise reservoir.
Brézin   +38 more
core   +1 more source

Generic Homeomorphisms with Shadowing of One-Dimensional Continua [PDF]

open access: yesAxioms, 2019
In this article, we show that there are homeomorphisms of plane continua whose conjugacy class is residual and have the shadowing property.
Alfonso Artigue, Gonzalo Cousillas
openaire   +7 more sources

Tracking Motor Progression and Device‐Aided Therapy Eligibility in Parkinson's Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To characterise the progression of motor symptoms and identify eligibility for device‐aided therapies in Parkinson's disease, using both the 5‐2‐1 criteria and a refined clinical definition, while examining differences across genetic subgroups.
David Ledingham   +7 more
wiley   +1 more source

The Impact of Tilburg Frailty on Poststroke Fatigue in First‐Ever Stroke Patients: A Cross‐Sectional Study With Unified Measurement Tools and Improved Statistics

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Poststroke fatigue (PSF) and frailty share substantial overlap in their manifestations, yet previous research has yielded conflicting results due to the use of heterogeneous frailty assessment tools. Objective To evaluate the independent impact of frailty on PSF using a unified measurement system (Tilburg Frailty Indicator, TFI ...
Chuan‐Bang Chen   +6 more
wiley   +1 more source

Discinesias induzidas por levodopa em 176 pacientes com doença de Parkinson Levodopa-induced dyskinesias in 176 parkisonian patients

open access: yesArquivos de Neuro-Psiquiatria, 1995
A ocorrência de discinesias dificulta consideravelmente o manuseio terapêutico dos pacientes parkinsonianos tratados com levodopa. Estudamos as características clínicas das discinesias em 176 pacientes com diagnóstico de doença de Parkinson e tratados ...
Maria Sheila G. Rocha   +3 more
doaj   +1 more source

Prediction Model for Etiologic Differentiation of Isolated Vestibular Syndrome in Emergency Settings

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective This study aimed to develop and validate a predictive model for differentiating central from peripheral etiologies in patients with isolated vestibular syndrome (VS). Methods In this multicenter retrospective cohort study, 506 patients with isolated VS from five hospitals were divided into derivation (n = 301) and validation (n = 205)
Guo Wenting   +12 more
wiley   +1 more source

Alternatives in modeling of body mass index as a continuous response variable and relevance of residual analysis Alternativas para modelagem do índice de massa corporal como variável contínua e relevância da análise de resíduos

open access: yesCadernos de Saúde Pública, 2008
This article presents alternatives for modeling body mass index (BMI) as a continuous variable and the role of residual analysis. We sought strategies for the application of generalized linear models with appropriate statistical adjustment and easy ...
Maria de Jesus Mendes da Fonseca   +4 more
doaj   +1 more source

Homogeneous ANR-spaces and Alexandroff manifolds

open access: yes, 2014
We specify a result of Yokoi \cite{yo} by proving that if $G$ is an abelian group and $X$ is a homogeneous metric $ANR$ compactum with $\dim_GX=n$ and $\check{H}^n(X;G)\neq 0$, then $X$ is an $(n,G)$-bubble.
Valov, V.
core   +1 more source

Impact of APOE ε4 Genotype Load on Cognitive Function and Lipid Metabolism in Patients With Cerebral Small Vessel Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Apolipoprotein ε4 (APOE ε4) is a potent genetic risk factor for Alzheimer's disease (AD). However, its role in cerebral small vessel disease (CSVD) remains unclear. Given the clinical and pathological similarities between CSVD and AD, this study aimed to investigate the associations of APOE ε4 gene dosage with cognitive function and
Tingru Jin   +6 more
wiley   +1 more source

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