Results 81 to 90 of about 28,002 (293)
Discovery and Targeted Proteomic Studies Reveal Striatal Markers Validated for Huntington's Disease
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Clinical trials for Huntington's disease (HD) enrolling persons before clinical motor diagnosis (CMD) lack validated biomarkers. This study aimed to conduct an unbiased discovery analysis and a targeted examination of proteomic biomarkers scrutinized by clinical validation. Methods Cerebrospinal fluid was obtained from PREDICT‐HD and
Daniel Chelsky +8 more
wiley +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Accurate localization of epileptogenic tubers (ETs) in patients with tuberous sclerosis complex (TSC) is essential but challenging, as these tubers lack distinct pathological or genetic markers to differentiate them from other cortical tubers.
Tinghong Liu +11 more
wiley +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Background Myasthenia gravis (MG) is an autoimmune disorder characterized by antibody‐mediated complement activation. Efgartigimod, a neonatal Fc receptor (FcRn) antagonist, is approved for treating generalized MG (gMG). However, its modulatory effects on upstream innate and adaptive immune cells remain largely unexplored.
Lei Jin +11 more
wiley +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Super‐Refractory Status Epilepticus (SRSE) is a rare, life‐threatening neurological emergency with unclear etiology in many cases. Mitochondrial dysfunction, often due to disease‐causing genetic variants, is increasingly recognized as a cause, with each gene producing distinct pathophysiological mechanisms.
Pouria Mohammadi +2 more
wiley +1 more source
Generalized Derivations With Left Annihilator Conditions in Prime and Semiprime Rings
Discussiones Mathematicae - General Algebra and Applications, 2017 Let R be a prime ring with its Utumi ring of quotients U, C = Z(U) be the extended centroid of R, H and G two generalized derivations of R, L a noncentral Lie ideal of R, I a nonzero ideal of R.
Dhara Basudeb
doaj +1 more source
Generalized Derivations and Rota-Baxter Operators of $n$-ary Hom-Nambu\n Superalgebras [PDF]
, 2020 Sami Mabrouk +2 more
openalex +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective The Gold Coast criteria permit diagnosis of amyotrophic lateral sclerosis (ALS) even without upper motor neuron (UMN) signs. However, whether ALS patients with UMN signs (ALSwUMN) and those without (ALSwoUMN) share similar characteristics and prognoses remains unclear.
Hee‐Jae Jung +7 more
wiley +1 more source
Characterization generalized derivations of tensor products of nonassociative algebras
Demonstratio MathematicaConsider A{\mathcal{A}} and ℬ{\mathcal{ {\mathcal B} }} to be nonassociative unital algebras. Under the assumption that either one of them has finite dimensions or that both are finite dimensions, a generalized derivation is an additive map ℱ:A→A ...
Aboubakr Ahmed
doaj +1 more source
Some spectral properties for generalized derivations [PDF]
, 2014 Mohamed Amouch, Farida Lombarkia
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