Results 41 to 50 of about 5,087 (229)

CLinNET: An Interpretable and Uncertainty‐Aware Deep Learning Framework for Multi‐Modal Clinical Genomics

open access: yesAdvanced Science, EarlyView.
Identifying disease‐causing genes in neurocognitive disorders remains challenging due to variants of uncertain significance. CLinNET employs dual‐branch neural networks integrating Reactome pathways and Gene Ontology terms to provide pathway‐level interpretability of genomic alterations.
Ivan Bakhshayeshi   +5 more
wiley   +1 more source

On the branched continued fraction expansions of the complete group of ratios of the generalized hypergeometric function $_4F_3$

open access: yesResearches in Mathematics
The paper considers the classical problem of the rational approximation of analytic functions of complex variable, in particulary, to issues that arise when constructing branched continued fraction expansions for generalized hypergeometric functions ...
Y. Lutsiv   +3 more
doaj   +1 more source

HiST: Histological Images Reconstruct Tumor Spatial Transcriptomics via MultiScale Fusion Deep Learning

open access: yesAdvanced Science, EarlyView.
HiST, a multiscale deep learning framework, reconstructs spatially resolved gene expression profiles directly from histological images. It accurately identifies tumor regions, captures intratumoral heterogeneity, and predicts patient prognosis and immunotherapy response.
Wei Li   +8 more
wiley   +1 more source

Single‐Cell Profiling Across Immune Tissues and Organs Reveals Immunosenescence Signatures in Male Rhesus Monkeys

open access: yesAdvanced Science, EarlyView.
Single‐cell profiling across bone marrow, spleen, mesenteric lymph, and blood in rhesus monkeys reveals organ Immunosenescence. GZMB rises with age, particularly in cytotoxic and terminally exhausted CD8+ T cells, and BHLHE40 emerges as a key transcription factor enriched across multiple CD8+ subsets, regulating pro‐inflammatory and exhaustion‐related ...
Shengnan Wang   +10 more
wiley   +1 more source

Three General Double-Series Identities and Associated Reduction Formulas and Fractional Calculus

open access: yesFractal and Fractional, 2023
In this article, we introduce three general double-series identities using Whipple transformations for terminating generalized hypergeometric 4F3 and 5F4 functions.
Mohd Idris Qureshi   +3 more
doaj   +1 more source

From Natural Discovery to AI‐Guided Design: A Curated Collection of Compact Enhancers for Crop Engineering

open access: yesAdvanced Science, EarlyView.
ABSTRACT Precise transgene‐free gene upregulation remains a challenge in crop biotechnology, as conventional enhancers often exceed CRISPR‐mediated knock‐in size constraints and face regulatory hurdles. Here we establish a foundational cross‐species resource of compact transcriptional enhancers developed via STEM‐seq, a high‐throughput screening ...
Qi Yao   +14 more
wiley   +1 more source

On Summations of Generalized Hypergeometric Functions with Integral Parameter Differences

open access: yesMathematics
In this paper, we present an extension of the Karlsson–Minton summation formula for a generalized hypergeometric function with integral parameter differences.
Kirill Bakhtin, Elena Prilepkina
doaj   +1 more source

Generalized Dirac Oscillator in Cosmic String Space-Time

open access: yesAdvances in High Energy Physics, 2018
In this work, the generalized Dirac oscillator in cosmic string space-time is studied by replacing the momentum pμ with its alternative pμ+mωβfμxμ. In particular, the quantum dynamics is considered for the function fμxμ to be taken as Cornell potential ...
Lin-Fang Deng   +3 more
doaj   +1 more source

Inequalities for some basic hypergeometric functions

open access: yesПроблемы анализа, 2019
We establish conditions for the discrete versions of logarithmic concavity and convexity of the higher order regularized basic hypergeometric functions with respect to the simultaneous shift of all its parameters.
Kalmykov S. I., Karp D. B.
doaj   +1 more source

Connection Problem for the Generalized Hypergeometric Function

open access: yesFunkcialaj Ekvacioj, 2021
We solve connection problem between fundamental solutions at singular points $0$ and $1$ for the generalized hypergeometric function, using analytic continuation of the integral representation. All connection coefficients are products of the sine and the cosecant.
Matsuhira, Y., Nagoya, H.
openaire   +2 more sources

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