Results 51 to 60 of about 6,079,712 (233)

On the Zeros of Some Generalized Hypergeometric Functions

Journal of Mathematical Analysis and Applications, 2000
The paper is concerned with the confluent hypergeometric function \[ F= {_pF_p}(a_1,\dots, a_p; b_1,\dots, b_p; z). \] It is assumed that the parameters are real, no numerator parameter equals zero or a negative integer, and the denominator parameters are positive.
Ki, Haseo, Kim, Young-One
openaire   +2 more sources

Gapless Complete Genome and Multi‐Omics Illuminate Immune Adaptation and Host‐Virus Interactions in a Coronavirus Reservoir

Advanced Science, EarlyView.
We present a complete T2T genome assembly for a key bat reservoir. Integrating population genomics, comparative genomics, transcriptomics, single‐cell omics, and functional assays, we resolve previously inaccessible genomic regions and identify evolutionary signatures associated with immune adaptation.
Yuting Wang, Sheng Zhang, Linxia Ouyang, Xin Du, Xin Huang, Zhilin Wang, Huixian Xie, Jiale Tang, Liyi Lou, Wenqing Ling, Weihao Wang, Jiang Zhou, Zhen Liu, Yibo Hu, Fuwen Wei, Guangping Huang   +15 more
wiley   +1 more source

Elucidating the MultiPathway Therapeutic Potential of Trichosantheskirilowii Bioactives in Intestinal Obstruction via Network Pharmacology and Molecular Dynamics [PDF]

ChemistryOpen
Network pharmacology identifies 31 shared targets linking T. kirilowii bioactives to intestinal obstruction, highlighting TNF, PI3K‐Akt, and MAPK signaling. Comparative docking, validation, and 100 ns molecular dynamics with MM/GBSA nominate β‐D‐glucopyranosyl‐α‐spinasterol as the leading candidate, binding albumin with the strongest predicted affinity
Wu T, Lin X, Lin W, Huang L, Lin Y.
europepmc   +2 more sources

Certain class of p-valent functions associated with the wright generalized hypergeometric function

, 2010
Using the Wright’s generalized hypergeometric function, we introduce a new ...
M. K. Aouf, A. Shamandy, S. M. Madian, A. O. Mostafa   +3 more
core   +1 more source

PHGDH‐Mediated Serine Metabolism in Nucleus Pulposus Cells Is a Potential Therapeutic Target for Intervertebral Disc Degeneration

Advanced Science, EarlyView.
When nucleus pulposus cells senesce, PHGDH decreases, reducing serine synthesis and glutathione, impairing antioxidant capacity. The intermediate α‐KG also drops, lowering JMJD3 demethylase activity, increasing H3K27me3 at the Rap1b promoter, and reducing Rap1b expression, whose down‐regulation in turn activates mTORC1 and suppresses autophagy ...
Hao‐Wei Xu, Sheng‐Jie Chang, Xiao‐Wei Liu, Shu‐Bao Zhang, Ying‐Jie Wang, Shan‐Jin Wang   +5 more
wiley   +1 more source

Integrals Involving Aleph Function and Wright’s Generalized Hypergeometric Function

, 2017
The aim of this paper is to establish certain integrals involving product of the Aleph function with Srivastava’s polynomials and Fox-Wright’s Generalized Hypergeometric function.
D.L. Suthar, Hagos Tadesse, Haile Habenom   +2 more
core   +1 more source

Dose‐related propofol resistance in COVID‐19 patients: Altered drug plasma levels, mechanistic insights from neuronal‐derived extracellular vesicles and miRNA analysis

British Journal of Clinical Pharmacology, EarlyView.
Abstract Aim Critical care for COVID‐19 patients presents unique challenges, particularly in sedation management. Patients demonstrate notable dose‐related resistance to propofol, potentially due to complex pharmacokinetic alterations. Emerging evidence suggests that plasma extracellular vesicle‐associated miRNA represents valuable predictive ...
Debora Curci, Carlotta Bidoli, Marco Gerdol, Charisse Winston, Robert A. Rissman, Giuliana Decorti, Antonella Fabretto, Andrea Taddio, Gabriele Stocco, Erik Roman‐Pognuz, Marianna Lucafò   +10 more
wiley   +1 more source

Acid‐Stable Nitrofuran Triple Therapy With Rabeprazole and Amoxicillin Targeting Helicobacter pylori Infection [PDF]

MedComm (2020)
Overview: Novel nitrofuran derivatives were developed and evaluated against Helicobacter pylori to overcome antibiotic resistance and inflammation. Methods and Findings: In vitro assays using H. pylori 60190 and PMSS1 strains demonstrated potent antibacterial activity, reduced bacterial adhesion, and inhibited cytokine release from gastric epithelial ...
Tharmalingam N, Arulsamy K, Lu S, Dhingra S, Goodrich S, Laurent J, Jones G, Mylonakis E.   +7 more
europepmc   +2 more sources

Some Properties of Extended Hypergeometric Function and Its Transformations

, 2018
There emerges different extended versions of Beta function and hypergeometric functions containing extra parameters. We obtain some properties of certain functions like extended Generalized Gauss hypergeometric functions, extended Confluent ...
Prakriti Rai, Aparna Chaturvedi
core   +1 more source

Increased Insulin Action, Glucose Metabolism and Muscle Function in Supervillin‐Knockout and Supervillin‐Mutant Mice

Cytoskeleton, EarlyView.
ABSTRACT We here describe mouse models with complementary homozygous Svil mutations. In skeletal muscle, Svil‐Mut mice express the Svil‐encoded N‐terminus fused to the βgal‐neo gene‐trap tag and lack the highly conserved archvillin C‐terminus; Svil‐KO mice lack expression of all known Svil‐encoded proteins; and Svil‐LoxP mice contain loxP sites for ...
Tara C. Smith, Lauren A. Tauer, Randall H. Friedline, Xiaodi Hu, Duy Tran, Yangyi E. Luo, Nacima Hadjout‐Rabi, Elisabeth R. Barton, Jason K. Kim, Elizabeth J. Luna   +9 more
wiley   +1 more source