Results 221 to 230 of about 90,344 (295)

Cuproptosis Signature Would Reveal the Acute‐Remitting Pattern in Patients with Neuromyelitis Optica Spectrum Disorder

open access: yesAdvanced Science, EarlyView.
Neuromyelitis optica spectrum disorder (NMOSD) has distinct acute‐remitting courses but lacks biomarkers for predicting relapse. Recent studies found cuproptosis‐related genes affect its course, and a model built accordingly can predict relapse to aid intervention.
Peidong Liu   +17 more
wiley   +1 more source

5’‐Methylthioadenosine Metabolic Reprogramming Drives H3K79 Monomethylation‐Mediated PAK2 Upregulation to Promote Cadmium‐Induced Breast Cancer Progression by Impairing Autophagic Flux

open access: yesAdvanced Science, EarlyView.
Cadmium, a carcinogenic heavy metal, drives breast cancer progression via metabolic reprogramming and autophagic flux disruption. Multi‐omics revealed cadmium‐induced 5'‐methylthioadenosine depletion activates DOT1L‐mediated H3K79me1 at PAK2 promoter, upregulating PAK2 to block autophagy and driving malignancy. Clinically, 5'‐methylthioadenosine levels
Jingdian Li   +24 more
wiley   +1 more source

Cut‐Enabled Mechanical Metamaterials for Multimodal and Reprogrammable Static Nonreciprocity

open access: yesAdvanced Science, EarlyView.
Cut‐enabled mechanical metamaterials are designed to overcome the challenge of obtaining multiple and reprogrammable static nonreciprocal modes in a single microstructural topology. It offers a pathway to synthesize multiple nonreciprocal modes and control the nonreciprocal responses, enhancing the functionality of metamaterials.
Jinhao Zhang   +8 more
wiley   +1 more source

Estimating preclinical amyloid positivity: A case study transporting ADNI to ARIC. [PDF]

open access: yesAlzheimers Dement (N Y)
Stapp EK   +10 more
europepmc   +1 more source

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