Results 31 to 40 of about 692,114 (266)

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

New generalized Fourier transforms and their applications to ordinary, partial and fractional differential equations

Miskolc Mathematical Notes
This article presents new generalized definitions of Fourier, Fourier sine, Fourier cosine, inverse Fourier, inverse Fourier sine and inverse Fourier cosine transforms, which encompass various studies on the generalized Fourier transforms in the existing
Enes Ata, İ. Onur Kıymaz
doaj   +1 more source

Miscellaneous equalities for idempotent matrices with applications

Open Mathematics, 2020
This article brings together miscellaneous formulas and facts on matrix expressions that are composed by idempotent matrices in one place with cogent introduction and references for further study.
Tian Yongge
doaj   +1 more source

Forward Order Law for the Reflexive Inner Inverse of Multiple Matrix Products

Axioms, 2022
The generalized inverse has numerous important applications in aspects of the theoretic research of matrices and statistics. One of the core problems of generalized inverse is finding the necessary and sufficient conditions for the reverse (or the ...
Wanna Zhou, Zhiping Xiong, Yingying Qin
doaj   +1 more source

Generalized Pseudolikelihood Methods for Inverse Covariance Estimation [PDF]

, 2016
We introduce PseudoNet, a new pseudolikelihood-based estimator of the inverse covariance matrix, that has a number of useful statistical and computational properties.
Ali, Alnur, Khare, Kshitij, Oh, Sang-Yun, Rajaratnam, Bala   +3 more
core   +2 more sources

Anomaly-free perturbations with inverse-volume and holonomy corrections in Loop Quantum Cosmology

, 2014
This article addresses the issue of the closure of the algebra of constraints for generic (cosmological) perturbations when taking into account simultaneously the two main corrections of effective loop quantum cosmology, namely the holonomy and the ...
Barrau, Aurelien, Cailleteau, Thomas, Linsefors, Linda   +2 more
core   +3 more sources

Screening for lung cancer: A systematic review of overdiagnosis and its implications

Molecular Oncology, EarlyView.
Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz, Laura de la Torre‐Perez, David R Baldwin, Carlijn van der Aalst, Mangesh Thorat, David Ritchie, Andre L Carvalho, Carolina Espina, Ivan Solà, Carlos Canelo‐Aybar, Moira Magdalena Pissinis, Pablo Alonso‐Coello, Ana Carolina Pereira Nunes Pinto   +12 more
wiley   +1 more source

Characterizations and properties of hyper-dual Moore-Penrose generalized inverse

AIMS Mathematics
In this paper, the definition of the hyper-dual Moore-Penrose generalized inverse of a hyper-dual matrix is introduced. Characterizations for the existence of the hyper-dual Moore-Penrose generalized inverse are given, and a formula for the hyper-dual ...
Qi Xiao, Jin Zhong
doaj   +1 more source

Randomized Dimension Reduction on Massive Data [PDF]

, 2013
Scalability of statistical estimators is of increasing importance in modern applications and dimension reduction is often used to extract relevant information from data.
Georgiev, Stoyan, Mukherjee, Sayan
core  

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

Molecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix, Daniel Samaga, Katharina Gehr, Benedek Dankó, Mohamed Schumann, Guido Drexler, Ahmed Alnatsha, Georg Beyer, Ujjwal Mahajan, Martin Selmansberger, Julia Mayerle, Claus Belka, Horst Zitzelsberger, Kirsten Lauber   +13 more
wiley   +1 more source