Results 31 to 40 of about 91,261 (245)

The Best Generalized Inverse

Journal of Mathematical Analysis and Applications, 2000
If \(A\) is an \(m\times n\) matrix, an approximate solution to the problem \(Ax=y\), is \(x=By\), where \(B\) is an \(n\times m\) matrix, and it is called a generalized inverse of \(A\). The Moore-Penrose generalized inverse of \(A\) (\(\widetilde{A}=(|A|_{\mid\text{range}(|A|)})^{-1}U^{\ast }\), where \(|A|=(A^{\ast }A)^{1/2}\) is the absolute value ...
Goldstein, Gisèle Ruiz, Goldstein, Jerome A   +1 more
openaire   +2 more sources

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

Molecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix, Daniel Samaga, Katharina Gehr, Benedek Dankó, Mohamed Schumann, Guido Drexler, Ahmed Alnatsha, Georg Beyer, Ujjwal Mahajan, Martin Selmansberger, Julia Mayerle, Claus Belka, Horst Zitzelsberger, Kirsten Lauber   +13 more
wiley   +1 more source

Trading off 1-norm and sparsity against rank for linear models using mathematical optimization: 1-norm minimizing partially reflexive ah-symmetric generalized inverses

Open Journal of Mathematical Optimization, 2021
The M-P (Moore–Penrose) pseudoinverse has as a key application the computation of least-squares solutions of inconsistent systems of linear equations. Irrespective of whether a given input matrix is sparse, its M-P pseudoinverse can be dense, potentially
Fampa, Marcia, Lee, Jon, Ponte, Gabriel
doaj   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Best linear unbiased estimation for varying probability with and without replacement sampling

Special Matrices, 2019
When sample survey data with complex design (stratification, clustering, unequal selection or inclusion probabilities, and weighting) are used for linear models, estimation of model parameters and their covariance matrices becomes complicated.
Haslett Stephen
doaj   +1 more source

Results on Resistance Distance and Kirchhoff Index of Graphs With Generalized Pockets

Frontiers in Physics, 2022
F, Hv are considered simple connected graphs on n and m + 1 vertices, and v is a specified vertex of Hv and u1, u2, … uk ∈ F. The graph G = G[F, u1, … , uk, Hv] is called a graph with k pockets, obtained by taking one copy of F and k copies of Hv and ...
Qun Liu, Jiaqi Li
doaj   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

Real‐World Investigation of Satralizumab in Patients With Neuromyelitis Optica Spectrum Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Satralizumab, a monoclonal antibody targeting the interleukin‐6 receptor, has demonstrated efficacy in clinical trials for neuromyelitis optica spectrum disorder (NMOSD). However, its real‐world effectiveness and safety compared to conventional immunosuppressive therapies remain uncertain.
Li‐Tsung Lin, Hui‐An Lin, Sheng‐Feng Lin   +2 more
wiley   +1 more source

Inverses and eigenvalues of diamondalternating sign matrices

Special Matrices, 2014
An n × n diamond alternating sign matrix (ASM) is a (0, +1, −1)-matrix with ±1 entries alternatingand arranged in a diamond-shaped pattern. The explicit inverse (for n even) or generalized inverse (for nodd) of a diamond ASM is derived.
Catral Minerva, Lin Minghua, Olesky D. D., van den Driessche P.   +3 more
doaj   +1 more source

Changes in Immune‐Inflammation Status and Acute Ischemic Stroke Prognosis in Prospective Cohort

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Inflammation is a critical risk factor for poor outcomes in cerebral infarction. Prior studies focused primarily on baseline inflammation status, neglecting dynamic longitudinal changes. We try to investigate the association between immune‐inflammation status alterations and stroke prognosis, and evaluated three systemic biomarkers'
Songfang Chen, Wenting Huang, Yitian Liu, Xuan Chen, Buyu Ke, Qian Shen, Hanyu Cai, Jing Sun, Yan Li, Yungang Cao, Beilei Hu, Keyang Chen   +11 more
wiley   +1 more source