Results 41 to 50 of about 691,972 (277)

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

Molecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak, Iva Staniczková Zambo, Matěj Přikryl, Peter Múdry, Danica Zapletalová, Jarmila Navrátilová, Jiří Navrátil, Jan Šmarda, Liudmyla Drobot, Petr Beneš, Lucia Knopfová   +10 more
wiley   +1 more source

Best linear unbiased estimation for varying probability with and without replacement sampling

Special Matrices, 2019
When sample survey data with complex design (stratification, clustering, unequal selection or inclusion probabilities, and weighting) are used for linear models, estimation of model parameters and their covariance matrices becomes complicated.
Haslett Stephen
doaj   +1 more source

The McCance Brain Care Score and Mortality: Evidence From a Large‐Scale Population‐Based Cohort

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives This study aimed to examine the relationship between the McCance Brain Care Score (BCS) and mortality in the general population. Methods We conducted a prospective, population‐based cohort study using data from the UK Biobank. Participants with complete data enabling calculation of BCS and full mortality information were included ...
Zhiqiang Xu, Xiaoxiao Wang, Nan Li
wiley   +1 more source

Asymptotic expansion for inverse moments of binomial and Poisson distributions

, 2005
An asymptotic expansion for inverse moments of positive binomial and Poisson distributions is derived. The expansion coefficients of the asymptotic series are given by the positive central moments of the distribution.
Znidaric, Marko
core   +2 more sources

Discovery and Targeted Proteomic Studies Reveal Striatal Markers Validated for Huntington's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Clinical trials for Huntington's disease (HD) enrolling persons before clinical motor diagnosis (CMD) lack validated biomarkers. This study aimed to conduct an unbiased discovery analysis and a targeted examination of proteomic biomarkers scrutinized by clinical validation. Methods Cerebrospinal fluid was obtained from PREDICT‐HD and
Daniel Chelsky, Cara Joyce, H. Jeremy Bockholt, Paul A. Rudnick, William H. Adams, Fiona McAllister, Justin W. Smock, Michael A. Newton, Jane S. Paulsen   +8 more
wiley   +1 more source

Inverses and eigenvalues of diamondalternating sign matrices

Special Matrices, 2014
An n × n diamond alternating sign matrix (ASM) is a (0, +1, −1)-matrix with ±1 entries alternatingand arranged in a diamond-shaped pattern. The explicit inverse (for n even) or generalized inverse (for nodd) of a diamond ASM is derived.
Catral Minerva, Lin Minghua, Olesky D. D., van den Driessche P.   +3 more
doaj   +1 more source

Parallel Sum of Bounded Operators with Closed Ranges

Mathematics, 2023
Let H be a separable infinite dimensional complex Hilbert space and B(H) be the set of all bounded linear operators on H. In this paper, we present several conditions under which the distributive law of the parallel sum is valid.
Wenting Liang
doaj   +1 more source

CX3CL1 in Early Detection of Alzheimer's Disease: Plasma Dynamics Across Age and Disease Stages

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Backgrounds Alzheimer's disease (AD) is characterized by amyloid‐beta plaques, tau tangles, and neuroinflammation. C‐X3‐C motif chemokine ligand 1 (CX3CL1, also known as fractalkine), a neuroimmune chemokine implicated in AD pathogenesis, shows inconsistent alterations in plasma/serum across studies.
Ling Wang, Yujie Liu, Fei Li, Xuelin Li, Lanlan Li, Jie Zhang, Yali Xu   +6 more
wiley   +1 more source

Some results on Drazin-Dagger matrices, reciprocal matrices, and conjugate EP matrices [PDF]

Journal of Mahani Mathematical Research
In this paper, a class of matrices, namely, Drazin-dagger matrices, in which the Drazin inverse andthe Moore-Penrose inverse commute, is introduced. Also, some properties of the generalized inverses of these matrices, are investigated.
Mahdiyeh Mortezaei, Gholamreza Aghamollaei   +1 more
doaj   +1 more source

Generalized Pseudolikelihood Methods for Inverse Covariance Estimation [PDF]

, 2016
We introduce PseudoNet, a new pseudolikelihood-based estimator of the inverse covariance matrix, that has a number of useful statistical and computational properties.
Ali, Alnur, Khare, Kshitij, Oh, Sang-Yun, Rajaratnam, Bala   +3 more
core   +2 more sources