Results 81 to 90 of about 1,034,308 (288)

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel   +14 more
wiley   +1 more source

Generalized Structured Component Analysis with Uniqueness Terms for Accommodating Measurement Error

Frontiers in Psychology, 2017
Generalized structured component analysis (GSCA) is a component-based approach to structural equation modeling (SEM), where latent variables are approximated by weighted composites of indicators.
Heungsun Hwang, Yoshio Takane, Kwanghee Jung   +2 more
doaj   +1 more source

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

Molecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak, Iva Staniczková Zambo, Matěj Přikryl, Peter Múdry, Danica Zapletalová, Jarmila Navrátilová, Jiří Navrátil, Jan Šmarda, Liudmyla Drobot, Petr Beneš, Lucia Knopfová   +10 more
wiley   +1 more source

The effects of facial appearance on measures of generalized trust

Scientific Reports
Research suggests various associations between generalized trust and a wide range of economic, political, and social dimensions. Despite its importance, there is considerable debate about how best to measure generalized trust.
Blaine G. Robbins, Maria S. Grigoryeva
doaj   +1 more source

Growth Modeling in a Diagnostic Classification Model (DCM) Framework–A Multivariate Longitudinal Diagnostic Classification Model

Frontiers in Psychology, 2020
A multivariate longitudinal DCM is developed that is the composite of two components, the log-linear cognitive diagnostic model (LCDM) as the measurement model component that evaluates the mastery status of attributes at each measurement occasion, and a ...
Qianqian Pan, Lu Qin, Neal Kingston
doaj   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

FEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Transient quantum fluctuation theorems and generalized measurements

New Journal of Physics, 2014
The transient quantum fluctuation theorems of Crooks and Jarzynski restrict and relate the statistics of work performed in forward and backward forcing protocols.
B Prasanna Venkatesh, Gentaro Watanabe, Peter Talkner   +2 more
doaj   +1 more source

Power Domination in the Generalized Petersen Graphs

Discussiones Mathematicae Graph Theory, 2020
The problem of monitoring an electric power system by placing as few measurement devices in the system can be formulated as a power dominating set problem in graph theory.
Zhao Min, Shan Erfang, Kang Liying
doaj   +1 more source

General Measures of Cognition

International Psychogeriatrics, 2003
A general cognitive performance battery is needed as a primary outcome in vascular dementia clinical trials. Because there is considerable overlap between vascular dementia and Alzheimer's disease (AD) in the pattern of cognitive impairment, a reasonable approach to developing an optimal vascular dementia battery is to begin with a widely used AD ...
openaire   +2 more sources