Results 91 to 100 of about 11,219 (248)

Study of differential cytokine IFN-γ,IL-10,TGF-β and IL-17 level in patients with myasthenia gravis with antibodies against AChR ,MuSK and LRP4 [PDF]

open access: yes, 2016
目的:通过采用酶联免疫吸附(ELISA)法检测重症肌无力(myastheniagravis,MG)患者血清乙酰胆碱受体抗体(AChR-Ab),肌肉特异性酪氨酸激酶抗体(MuSK-Ab),低密度脂蛋白受体相关蛋白4抗体(LRP4-Ab)浓度,探讨AChR-Ab,MuSK-Ab,LRP4-Ab与重症肌无力临床分型、及与细胞因子干扰素-γ(IFN-γ),白细胞介素-10(IL-10),生长转化因子-β(TGF-β),白细胞介素-17(IL-17)的关系。 方法: 1.本研究分为重症肌无力组和健康对照组 ...
李若冰
core  

Review Article : Neuromuscular causes of weakness in critically ill patients [PDF]

open access: yes, 2017
Multiple predisposing factors are responsible for the development of neuromuscular weakness in a critically ill patient. Thorough history and physical examination is paramount and should not be omitted despite that the majority of patients are ...
Govindarajan, Raghav, Katyal, Nakul
core   +1 more source

Retrospective Evaluation of Dual Specialty Ports in Therapeutic Apheresis

open access: yesJournal of Clinical Apheresis, Volume 41, Issue 3, June 2026.
ABSTRACT Dual specialty ports were evaluated for safety and efficacy in therapeutic apheresis by analyzing outcomes across 97 port placement events in 88 patients, focusing on two configurations: dual Bard PowerFlow (BP2) and a combination of Bard PowerFlow with AngioDynamics SmartPort (BP + AD).
Mugtaba Swar‐Eldahab   +3 more
wiley   +1 more source

MuSK Antibody Positive Myasthenia Gravis Mimicking as Myositis

open access: yesMedical Journal of Dr. D.Y. Patil Vidyapeeth
Most common neuromuscular junction disorder is Myasthenia gravis (MG) which has variable clinical presentations. Diplopia and drooping of eyelids are the peculiarity of myasthenia gravis.
Nilesh Wagh   +4 more
doaj   +1 more source

Quality of life and life circumstances in German myasthenia gravis patients [PDF]

open access: yes, 2010
Background Myasthenia gravis (MG) is a chronic neuromuscular disease. Advances in medical therapy have continuously increased the life expectancy of MG patients, without definitively curing the disease.
Sabine Twork   +4 more
core   +2 more sources

Heme Metabolism‐Derived Carbon Monoxide Regulates Skeletal Muscle Function

open access: yesJournal of Cachexia, Sarcopenia and Muscle, Volume 17, Issue 3, June 2026.
ABSTRACT Background Heme oxygenases, HO‐1 (Hmox1) and HO‐2 (Hmox2), regulate skeletal muscle homeostasis by degrading heme and generating carbon monoxide (CO), a bioactive signalling molecule. Although HO‐1 is known to influence muscle fibre composition and mitochondrial function, the role of HO‐2 in activity‐dependent neuromuscular plasticity remains ...
Rodrigo W. Alves de Souza   +8 more
wiley   +1 more source

Response of patients with refractory myasthenia gravis to rituximab: a retrospective study

open access: yesTherapeutic Advances in Neurological Disorders, 2011
Introduction: Myasthenia gravis, an autoimmune disorder of neuromuscular transmission, is treated by an array of immunomodulating therapies. A variable response is observed with certain patients being medically refractory.
Richard J. Nowak   +3 more
doaj   +1 more source

Class A drug abuse: an ophthalmologist's problem? [PDF]

open access: yes, 2005
[First Paragraph] The 2002/3 British Crime Survey reported that 3% of all 16 to 59 year olds (equating to around one million people) had used a class A drug in the last year.
Firth, A.Y.
core   +1 more source

Experience Using Efgartigimod to Treat Juvenile Myasthenia Gravis in China: A Multicenter Retrospective Study

open access: yesMuscle &Nerve, Volume 73, Issue 6, Page 1025-1031, June 2026.
ABSTRACT Introduction/Aims Current therapeutic management of juvenile myasthenia gravis (JMG) predominantly relies on conventional immunosuppressive therapies and expert consensus extrapolated from adult data, creating a critical gap in high‐quality, pediatric‐specific clinical evidence.
Jing Lin   +14 more
wiley   +1 more source

Subcutaneous batoclimab in generalized myasthenia gravis: Results from a Phase 2a trial with an open‐label extension

open access: yesAnnals of Clinical and Translational Neurology
Objectives To assess the safety, tolerability, and key pharmacodynamic effects of subcutaneous batoclimab, a fully human anti‐neonatal Fc receptor monoclonal antibody, in patients with generalized myasthenia gravis and anti‐acetylcholine receptor ...
Richard J. Nowak   +12 more
doaj   +1 more source

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