Results 1 to 10 of about 67,727 (164)

Assessment of the risks of a myasthenic crisis after thymectomy in patients with myasthenia gravis: a systematic review and meta-analysis of 25 studies

Journal of Cardiothoracic Surgery, 2020
Background Despite the burgeoning literature describing preoperative and postoperative risks of a myasthenic crisis after thymectomy (MCAT) in patients with myasthenia gravis, substantial differences exist in the risk factors identified by previous ...
Chaoying Liu, Peng Liu, Xiao jing Zhang, Wen qian Li, Guoyan Qi   +4 more
doaj   +1 more source

Identification of Potential Serum Protein Biomarkers in Thymoma with Myasthenia Gravis After Docetaxel Treatment

Neurology and Therapy, 2023
Introduction Myasthenia gravis (MG) is a devastating acquired autoimmune disease that can seriously affect the patient’s quality of life. It is also a common complication of thymoma.
Hongxia Yang, Guoyan Qi, Huimin Dong, Ze Liu, Mei Ma, Peng Liu   +5 more
doaj   +1 more source

Metagenome-wide association study of gut microbiome revealed potential microbial marker set for diagnosis of pediatric myasthenia gravis

BMC Medicine, 2021
Background Myasthenia gravis (MG) is an acquired immune-mediated disorder of the neuromuscular junction that causes fluctuating skeletal muscle weakness and fatigue. Pediatric MG and adult MG have many different characteristics, and current MG diagnostic
Peng Liu, Yiqi Jiang, Shanshan Gu, Yinping Xue, Hongxia Yang, Yongzhao Li, Yaxuan Wang, Congya Yan, Pei Jia, Xiaoting Lin, Guoyan Qi   +10 more
doaj   +1 more source

Anxiety and depression in thymoma patients in China before surgery

Journal of Cardiothoracic Surgery, 2022
Background The study's goal was to investigate the percentage of anxiety and depression in Chinese thymoma patients before surgery, and also the factors that influence it.
Jiaduo Li, Guoyan Qi, Yaling Liu
doaj   +1 more source

Long-term efficacy and safety of eculizumab in Japanese patients with generalized myasthenia gravis : a subgroup analysis of the REGAIN open-label extension study [PDF]

, 2019
The terminal complement inhibitor eculizumab was shown to improve myasthenia gravis-related symptoms in the 26-week, phase 3, randomized, double-blind, placebo-controlled REGAIN study (NCT01997229).
De Bleecker, Jan, Fujita, KP, Imai, T, Murai, H, O'Brien, F, Okumura, M, Shiraishi, H, Study Group, REGAIN, Suzuki, H, Suzuki, Y, Utsugisawa, K, Uzawa, A, Wang, JJ   +12 more
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Ocular myasthenia

Neurologijos seminarai, 2022
Myasthenia gravis is a chronic autoimmune neuromuscular disorder typically presenting with variable skeletal muscle fatigue. The most prevalent initial manifestation of myasthenia is ocular myasthenia.
J. Zakaravičiūtė, M. Šerelytė
doaj   +1 more source

A phase 3 multicenter, prospective, open-label efficacy and safety study of immune globulin (human) 10% caprylate/chromatography purified in patients with myasthenia gravis exacerbations [PDF]

, 2019
Background: Myasthenia gravis (MG) is an autoimmune disorder affecting neuromuscular transmission. Exacerbations may involve increasing bulbar weakness and/or sudden respiratory failure, both of which can be critically disabling.
Ayguasanosa, J, Balasa, R, Bril, V, Camprubi, S, Chen, J, De Bleecker, Jan, Garcia, B, Griffin, R, Heckmann, JM, Henriquez, W, Karelis, G, Lagrange, E, Mondou, E, Nicolle, M, Stuchevskaya, T, Van Damme, P, Vilciu, C, Villa, A   +17 more
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The burden of myasthenia gravis – highlighting the impact on family planning and the role of social support

Frontiers in Neurology, 2023
BackgroundMyasthenia gravis (MG) is a rare autoimmune disease and chronic condition that necessitates specialized care. Patients experience a significant burden of disease affecting various aspects of their lives. The aim of this study was to investigate
Maike Stein, Maike Stein, Maike Stein, Maike Stein, Ulrike Grittner, Ulrike Grittner, Regina Stegherr, Lea Gerischer, Lea Gerischer, Frauke Stascheit, Frauke Stascheit, Sarah Hoffmann, Sarah Hoffmann, Meret Herdick, Meret Herdick, David Legg, Derin Marbin, Derin Marbin, Andreas Meisel, Andreas Meisel, Andreas Meisel, Sophie Lehnerer, Sophie Lehnerer, Sophie Lehnerer, Sophie Lehnerer   +24 more
doaj   +1 more source

Congenital Myasthenic Syndrome: case study from a tertiary care institute of Western India [PDF]

Romanian Journal of Neurology, 2023
Objective. To describe clinical characteristics, genetic details and management of patients of congenital myasthenic syndrome. Methods. A retrospective study was carried out from 2020 to 2023.
Parag R. Maheshkar, Koustubh Bavdhankar, Neeraj Jain, Rishikesh Joshi, Santosh Sriram Andugulapati   +4 more
doaj   +1 more source

Relationship between hearing function and myasthenia gravis: a contemporary review [PDF]

, 2016
There is increasing evidence of a connection between hearing function and myasthenia gravis (MG). Studies of the pathophysiological basis of this relationship suggest that acetylcholine receptors (AChRs) on outer hair cells (OHCs) play a central role. In
ALTISSIMI, Giancarlo, CIANFRONE, Giancarlo, DI STADIO, Arianna, MAZZEI, FILIPPO, RALLI, MASSIMO, TURCHETTA, Rosaria   +5 more
core   +1 more source