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Case report: Successful perioperative intervention with efgartigimod in a patient in myasthenic crisis [PDF]
Frontiers in ImmunologyIntroductionThis case describes successful response to efgartigimod in the treatment of myasthenic crisis secondary to paraneoplastic disease, and in the perioperative setting.MethodsAn elderly female presented with speech difficulties, cessation of ...
Shahar Shelly
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Case report: Recovery from refractory myasthenic crisis to minimal symptom expression after add-on treatment with efgartigimod [PDF]
Frontiers in NeurologyMyasthenic crisis, a life-threatening exacerbation of myasthenia gravis, is a significant clinical challenge, particularly when refractory to standard therapies.
Keiko Watanabe +4 more
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Myasthenic Crisis In Pregnancy [PDF]
Clinical Practice and Cases in Emergency Medicine, 2017 This case reviews the management of a 27-year-old pregnant female in myasthenic crisis. She presented to the emergency department in respiratory distress refractory to standard therapy, necessitating airway and ventilatory support and treatment with ...
David M. French +4 more
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Neurological Research and Practice, 2019 Introduction The overall prevalence of myasthenic crisis is quite low at 30/1 million inhabitants because myasthenia gravis is a rare disease per se. But it should be noted that 15–20% of patients with myasthenia gravis experience at least one crisis in ...
Henning Stetefeld, Michael Schroeter
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Muscle and Nerve, 2023 AbstractMyasthenic crisis (MC) is a life‐threatening manifestation of myasthenia gravis (MG) defined by respiratory insufficiency that requires the use of invasive or non‐invasive ventilation. This is often the result of respiratory muscle weakness but can also be due to bulbar weakness with upper airway collapse.
Benjamin Claytor +2 more
exaly +3 more sources
Occurrence and severity of myasthenic crisis in an unselected Turkish cohort of patients with myasthenia gravis [PDF]
Frontiers in Neurology, 2023 Myasthenia gravis (MG) is a disorder of the neuromuscular junction that can deteriorate into myasthenic crisis, involving weakness of bulbar and respiratory muscles.
Selen Ozyurt Kose +4 more
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Pulmonary Edema in Myasthenic Crisis [PDF]
Case Reports in Critical Care, 2013 We report a previously asymptomatic 50-year-old lady who came with myasthenic crisis as initial presentation of myasthenia gravis. She developed pulmonary edema following intravenous immunoglobulin administration and had ischemic changes in ECG and left ...
Uttara Swati Anand +2 more
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Efficacy and safety of efgartigimod in the treatment of impending myasthenic crisis [PDF]
Frontiers in ImmunologyObjectiveTo compare the short-term efficacy and safety of efgartigimod versus intravenous immunoglobulin (IVIg) in patients with impending myasthenic crisis (IMC).MethodsThis single-center, randomized, open-label, prospective comparative cohort study ...
Ning Li +11 more
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Weaning from mechanical ventilation during myasthenic crisis, a monocentric retrospective study [PDF]
Scientific ReportsMechanical ventilation in myasthenic crisis is not standardized and is at high risk of failure. We investigated liberation from mechanical ventilation during myasthenic crisis using a prolonged spontaneous breathing trials (SBT) and sequential pulmonary ...
Aurélien Mazeraud +11 more
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Efgartigimod combined with steroids as a fast-acting therapy for myasthenic crisis: a case report [PDF]
BMC NeurologyBackground Generalized myasthenia gravis (gMG) can be managed with acetylcholinesterase inhibitors (AChEis; e.g., pyridostigmine), corticosteroids, other immunosuppressive drugs (e.g., tacrolimus), and their combinations. Intravenous immunoglobulin (IVIg)
Hiroya Ohara +3 more
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