Results 51 to 60 of about 11,219 (248)

Long-term safety and efficacy of eculizumab in generalized myasthenia gravis [PDF]

, 2019
Introduction: Eculizumab is effective and well tolerated in patients with antiacetylcholine receptor antibody-positive refractory generalized myasthenia gravis (gMG; REGAIN; NCT01997229). We report an interim analysis of an open-label extension of REGAIN,
Andersen, Henning, Barohn, Richard J, Benatar, Michael, Burns, Ted M, Casasnovas, Carlos, De Bleecker, Jan, Fujita, Kenji P, Howard, James F, Jr., Illa, Isabel, Jacob, Saiju, Kissel, John T, Mantegazza, Renato, Muppidi, Srikanth, Murai, Hiroyuki, Nowak, Richard J, O'Brien, Fanny L, Utsugisawa, Kimiaki, Vissing, John, Vu, Tuan H, Wang, Jing Jing   +19 more
core   +2 more sources

CAR T‐Cell Therapy in Neurology: A Scoping Review of Neuro‐Oncology, Autoimmune Diseases & Neurotoxicity

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Chimeric antigen receptor (CAR) T‐cell therapy has been investigated in neurological diseases, encompassing both central nervous system malignancies and autoimmune disorders, thereby extending its application beyond hematological cancers.
Omar Alqaisi, Mohammed Dibas, Patricia Tai, Ala Dibas, Osama Souied, Suhair Al‐Ghabeesh   +5 more
wiley   +1 more source

Spotlight on MuSK positive myasthenia gravis: clinical characteristics, treatment and outcomes

BMC Neurology, 2022
Background To investigate the clinical characteristics, treatments and outcomes of patients with myasthenia gravis with antibodies to muscle-specific tyrosine kinase (MuSK-MG).
Qi Huang, Feng Li, Song Zhao
doaj   +1 more source

Immune Checkpoint Inhibitor–Related Myositis and Associated Triad Overlap Syndrome

Arthritis Care &Research, EarlyView.
Objective Immune checkpoint inhibitor (ICI) myositis is a rare but a highly morbid condition, particularly with the ICI myositis triad syndrome of myositis, myocarditis, and myasthenia gravis. We report the clinical characteristics of ICI myositis and all‐cause mortality in these patients.
Selene Rubino, Grant W. Cannon, Brian C. Sauer, Jorge Rojas, Gregory J. Stoddard, Gary A. Kunkel, Jessica A. Walsh, Bryant R. England, Joshua F. Baker, Tawnie J. Braaten   +9 more
wiley   +1 more source

Delayed diagnosis of distal myasthenia gravis: a case report

Journal of Medical Case Reports
Introduction Myasthenia gravis, which initially presents with prominent distal muscle weakness, is rare and is referred to as distal myasthenia gravis.
M. L. Cao, Y. X. Qin, N. Shao, C. Y. Zhang, L. L. Deng, X. R. Xu, Q. Liu, X. Yang   +7 more
doaj   +1 more source

Brazilian cross-cultural translation and adaptation of the Questionnaire of Life Quality Specific for Myasthenia Gravis-15 items [PDF]

, 2013
Objective: To translate and to perform the cross-cultural adaptation of the Questionnaire of Life Quality Specific for Myasthenia Gravis - 15 items (MG-QOL15). Method: the original English version of the questionnaire was translated into Portuguese. This
Araujo, Caroline Martins, Barbosa, Luiz Sergio Mageste, Burns, Ted M., Gomez, Rodrigo Santiago, Lemos, Stela Maris Aguiar, Mourao, Aline Mansueto, Teixeira, Antonio Lúcio   +6 more
core   +2 more sources

Prognostic factors for conversion to generalization in ocular myasthenia gravis

Medicine, 2021
Abstract Patients with ocular myasthenia gravis (OMG) are frequently treated to prevent the development of generalized myasthenia gravis (GMG). This retrospective cohort study aimed to assess prognostic factors associated with conversion to GMG.
Juthamat Witthayaweerasak, Narisa Rattanalert, Nipat Aui-aree   +2 more
openaire   +2 more sources

Autoimmune Encephalitis in Acute Care—Pathology, Diagnosis, and Management

Advanced Science, EarlyView.
ABSTRACT Autoimmune encephalitis (AE) is characterized by immune‐mediated inflammation of the brain parenchyma, presenting with various neurological syndromes, including but not limited to seizures, altered consciousness, neuropsychiatric symptoms, and movement disorders.
Suneesh Thilak, David Okoh, William Scotton, Shanika Samarasekera, Vikram Patil, Suresh Renukappa, Andrew Macduff, Subashini Suresh, Rajeev Krishnadas, Tonny Veenith   +9 more
wiley   +1 more source

The evaluation of approaches to the treatment of myasthenia gravis.

Medičnì Perspektivi, 2019
Myasthenia gravis is a relatively rare autoimmune disease with an undetermined aetiology which affects neuromuscular junctions. Currently, the following approaches to the treatment of myasthenia gravis are mainly distinguished: symptomatic treatment with
O. I. Kalbus, N. P. Shastun, S. O. Makarov, Yu. V. Bukreyeva, O. V. Somilo   +4 more
doaj   +1 more source

Posterior reversible encephalopathy syndrome following septicemia in patient with myasthenia gravis

Radiology Case Reports, 2023
Posterior reversible encephalopathy syndrome is a clinicoradiologic entity characterized by seizure, headaches, visual symptoms, impaired consciousness, and vasogenic cerebral edema of occipital and parietal lobes of the brain. Magnetic resonance imaging
Pham Dang Hai, MD, Vu Anh Duc, MD, Vu Quang Hung, MD, Nguyen Van Viet Thang, MD   +3 more
doaj   +1 more source