Results 81 to 90 of about 124,673 (292)

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

ON (?,?)-CLOSED SETS IN GENERALIZED TOPOLOGICAL SPACES [PDF]

open access: yes, 2011
In this paper, we introduce and study (Lambda, mu)-open sets and (Lambda, mu)-closed sets via mu-open and mu-closed sets in generalized topological spaces.
Ekici, Erdal, Roy, Bishwambhar
core  

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

SOFT π-OPEN SETS IN SOFT GENERALIZED TOPOLOGICAL SPACES

open access: yesJournal of New Theory, 2015
The main purpose of this paper is to study some interesting properties of the soft mapping π : S(U)E → S(U)E which satisfy the condition πFB ⊂ πFD whenever FB ⊂ FD ⊂ ̃.
Jyothis Thomas, Sunil Jacob John
doaj  

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau   +8 more
wiley   +1 more source

On $\tilde{\mu}$-open sets in generalized topological spaces

open access: yesMalaya Journal of Matematik, 2015
In this paper, we introduce the notion of $\tilde{\mu}$-open sets in generalized topological spaces. Further, we introduce the notions of interior, closure, boundary, exterior and study some of their properties. In addition, we introduce the concepts of $\tilde{\mu}-T_i\left(i=0, \frac{1}{2}, 1,2\right)$ spaces are characterized them using $\tilde{\mu}$
Saravanakuma, D.   +2 more
openaire   +2 more sources

Generalized open sets in soft topological spaces

open access: yes, 2014
Fen Bilimleri Enstitüsü, Matematik Ana Bilim DalıGenelleştirilmiş esnek kümeleri ve genelleştirilmiş esnek topolojik yapıları incelemeyi amaçlayan bu çalışma yedi bölümden oluşmaktadır.
Özkan, Alkan
core  

PS-Regular Sets in Topology and Generalized Topology [PDF]

open access: yes, 2014
We define and study a new class of regular sets called PS-regular sets. Properties of these sets are investigated for topological spaces and generalized topological spaces. Decompositions of regular open sets and regular closed sets are provided using PS-
Ankit Gupta, Ratna Dev Sarma
core   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner   +14 more
wiley   +1 more source

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