On an Approximate Solution Method for the Problem of Surface and Groundwater Combined Movement with Exact Approximation on the Section Line [PDF]
In this paper, the initial-boundary problem for two nonlinear parabolic combined equations has been considered. One of the equations is set on the bounded domain Ω from R2, another equation is set along the curve lying in Ω.
L.L. Glazyrina, M.F. Pavlova
doaj
The human gut microbiome across the life course
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero +4 more
wiley +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Design and analysis strategies for robust microbiome ageing research
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Symbolic solution of Generalized Kepler Õs Equation
Kepler's generalized equation is a transcendental nonlinear equation that must be solved in order to compute the position and velocity of an artificial satellite at any instant t.
Abad, A. [0000-0002-5692-5876] +1 more
core +1 more source
Solvability of a nonlocal problem for a hyperbolic equation with degenerate integral conditions
In this paper, we consider a nonlocal problem with integral conditions for hyperbolic equation. Close attention focuses on degenerate integral conditions, namely, on the second kind integral conditions which degenerate into the first kind conditions at ...
Ludmila Stepanovna Pulkina +1 more
doaj +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Nonlocal approach to problems on longitudinal vibration in a short bar
In this article, we consider a problem with dynamic nonlocal conditions for a forth-order PDE with dominating mixed derivative. This problem is closely related to vibration problems, in particular, to longitudinal vibration in a short bar.
Ludmila S. Pulkina, Alexander B. Beylin
doaj
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Paradigmatic well posedness in some generalized characteristic Cauchy problems [PDF]
By means of convenient regularization for an ill posed Cauchy problem, we deï¬ne an associated generalized problem and discuss the conditions for the solvability of it.
Emmanuel Allaud +4 more
core

