Results 141 to 150 of about 24,565 (251)

Solitary Neurocysticercosis Presenting with Focal Seizure and Secondary Generalized Tonic-Clonic Seizure. [PDF]

open access: yesAm J Case Rep, 2022
Yingchoncharoen P   +5 more
europepmc   +1 more source

Do witnesses of functional/dissociative seizures recall them accurately? A UK experimental study of semiology recall at clinically relevant time points with a pilot intervention

open access: yesEpilepsia, EarlyView.
Abstract Objective Different causes of transient loss of consciousness (TLOC) carry distinct risks and require different management. Early accurate diagnosis is essential to guide counseling, investigation, and referral. In routine practice, frontline clinicians and specialists often rely on eyewitness accounts, yet the reliability of witness testimony
Adam John Noble   +11 more
wiley   +1 more source

Reduction of generalized tonic-clonic seizures following vagus nerve stimulation therapy: CORE-VNS Study 24-month follow-up. [PDF]

open access: yesEpilepsia
Suller Marti A   +9 more
europepmc   +1 more source

Ventral anterior thalamic dysfunction distinguishes seizure generalization in temporal lobe epilepsy

open access: yesEpilepsia, EarlyView.
Abstract Objective Focal‐to‐bilateral tonic–clonic seizures (FBTCS) in temporal lobe epilepsy (TLE) involve thalamocortical networks, yet the functional integrity and role of specific thalamic subregions in seizure generalization remain unclear. In this cross‐sectional study, we investigated whether thalamic subregion functional connectivity patterns ...
Stacy N. Hudgins   +3 more
wiley   +1 more source

Epilepsy‐associated SCN2A‐L1342P mutation drives network hyperexcitability and widespread transcriptomic changes in human cortical organoids

open access: yesEpilepsia, EarlyView.
Abstract Objective SCN2A pathogenic mutations, such as the recurrent heterozygous Nav1.2‐L1342P, are monogenic causes of epilepsy. In this human‐induced pluripotent stem cell–derived model system, we aim to investigate the molecular and cellular mechanisms underlying SCN2A‐L1342P‐associated pathology. Methods Using a human male induced pluripotent stem
Maria I. Olivero‐Acosta   +26 more
wiley   +1 more source

Characterizing chapeau de gendarme in pediatric epilepsy through systematic video‐EEG evaluation

open access: yesEpilepsia, EarlyView.
Abstract Objective Chapeau de gendarme (CdG) is a subtle but clinically relevant semiology that has been scarcely studied in children. Previous studies have primarily focused on its localizing value in small, surgical cohorts. This study aimed to systematically characterize frequency and clinical features of CdG across the pediatric age spectrum ...
Hanna Barbara Brinkmann   +5 more
wiley   +1 more source

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