Results 161 to 170 of about 826,950 (244)

Theory of mind: A cognitive endophenotype of juvenile myoclonic epilepsy?

Epilepsia, EarlyView.
Abstract Objective Juvenile myoclonic epilepsy (JME), the most common idiopathic generalized epilepsy, is associated with neuropsychological and psychiatric comorbidities, including social cognition and theory of mind (ToM) deficits. The interplay between clinical features, social cognition, and their neural and genetic substrates remains poorly ...
Bernardo Crespo‐Pimentel, Lucas J. Rainer, Mario Braun, Martin Kronbichler, Patrick Langthaler, Lisa Kronbichler, Sarah Said‐Yürekli, Laura Zamarian, Hennric Jokeit, Kornelius Winds, Elias Legat, Eugen Trinka, Julia Höfler, Giorgi Kuchukhidze   +13 more
wiley   +1 more source

Diabetic Ketoacidosis Presenting With New-Onset Generalized Tonic-Clonic Seizures and Status Epilepticus in a Previously Undiagnosed Diabetic Patient: A Case Report. [PDF]

Cureus
Aziouaz F, Kaadan D, Ftouh W, Dakkon Y, Benkacem M.   +4 more
europepmc   +1 more source

Bilateral shoulder pain after a generalized tonic-clonic seizure: case report of an acute undiagnosed bilateral fracture of proximal humerus

, 2014
Bilateral shoulder fracture is a rare event and convulsive epileptic seizure is one of the most common causes. Detailed physical and neurovascular examination are important but shoulder’s antero- posterior and axillary radiographs are essential to reveal
ANDREANI, LORENZO, LISANTI, MICHELE, CASTELLINI, IACOPO, ZARRA, VERONICA, Enrico Bonicoli   +4 more
core  

Multimodal modeling of the ictal onset zone in refractory insular epilepsy and seizure outcome of magnetic resonance‐guided laser interstitial therapy: A pediatric single‐center retrospective study

Epilepsia, EarlyView.
AbstractObjectiveThis study was undertaken to evaluate seizure outcomes after magnetic resonance‐guided laser interstitial thermal therapy (MRgLITT) in children with insular epilepsy and to assess how the extent of ablation overlaps with multimodal definitions of the ictal onset zone (IOZ).MethodsWe conducted a retrospective, single‐center study ...
Lelio Guida, Emma Losito, Sebastian Rodrigo, Catherine Chiron, Ludovic Fillon, Marie Bourgeois, Anna Kaminska, Johan Pallud, Nicole Chemaly, Volodia Dangouloff‐Ross, Stephane Aunvin, Blandine Dozieres, Rima Nabbout, Olivier David, Nathalie Boddaert, Thomas Blauwblomme   +15 more
wiley   +1 more source

Efficacy and safety of perampanel as first adjunctive therapy in patients with focal-onset seizures or generalized tonic-clonic seizures in four post-marketing studies across regions. [PDF]

Epilepsia Open
Meletti S, Punia V, Dash A, Gentile AL, Sáinz-Fuertes R, Goldman S, Goldmann T, Patten A, Kumar D, Ngo LY, Steinhoff BJ.   +10 more
europepmc   +1 more source

Eslicarbazepine Acetate as Adjunctive Therapy for Primary Generalized Tonic-Clonic Seizures in Adults: A Prospective Observational Study. [PDF]

CNS Drugs, 2022
Winter Y, Sandner K, Vieth TL, Melzer N, Klimpe S, Meuth SG, Groppa S.   +6 more
europepmc   +1 more source

Fenfluramine treatment and seizure‐free days in pediatric and adult patients with Lennox–Gastaut syndrome: A post hoc analysis

Epilepsia, EarlyView.
This graphical abstract provides an overview of the post hoc analysis evaluating change in percentage of seizure‐free days in pediatric and adult patients treated with fenfluramine in the Lennox‐Gastaut syndrome phase 3 study. Abstract The most common primary endpoint for assessing treatment efficacy in patients with Lennox–Gastaut syndrome (LGS) is ...
Stéphane Auvin, Ingrid E. Scheffer, Antonio Gil‐Nagel, Patrick Healy, Amélie Lothe, Mélanie Langlois, Jayne Abraham, Lieven Lagae, Kelly G. Knupp   +8 more
wiley   +1 more source

In-hospital evaluation of an app-based seizure detection system in dogs: timely detection of generalized tonic-clonic seizures. [PDF]

Front Vet Sci
Hirashima J, Saito M, Hasegawa D, Asada R, Kitagawa M, Ito D, Kanazono S, Fujiwara K.   +7 more
europepmc   +1 more source

Wilson's Disease Presenting with Generalized Tonic-Clonic Seizure and Cerebellar Dysfunction. [PDF]

Int Med Case Rep J, 2021
Rasib AR, Aziz Jabarkhil A, Sediqi MF, Mansoor AI, Asady A.   +4 more
europepmc   +1 more source

Selective γ8 transmembrane α‐amino‐3‐hydroxy‐5‐methyl‐4‐isoxazolepropionic acid receptor regulatory protein negative allosteric modulators: Efficacy in preclinical antiseizure models

Epilepsia, EarlyView.
Abstract Objective RAP‐219, a potent selective negative allosteric modulator (NAM) of α‐amino‐3‐hydroxy‐5‐methyl‐4‐isoxazolepropionic acid receptor (AMPAR) associated with γ8 transmembrane AMPAR regulatory protein (TARPγ8), is in phase 3 development for refractory focal epilepsy. This study was undertaken to assess efficacy and motor function following
Jose A. Matta, Brock T. Shireman, Laurie P. Volak, Michael P. Maher, Michael K. Ameriks, David Bredt   +5 more
wiley   +1 more source