Results 131 to 140 of about 495,921 (307)

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

Molecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach, Gizem Abaci, Tom Huberty, Axel Lechner, Lukas Käsmann, Jens Ricke, Sophia Stöcklein, Martin Canis, Philipp Baumeister, Marianna Alunni‐Fabbroni   +9 more
wiley   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Interval forecasting of renewable power generation

, 2018
With the development of renewable power generation, forecasting of renewable power generation output is significant for modern power grids. Solar power generation, which is the important component of renewable power generation, is selected as the ...
Luo, Lingfeng
core  

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

A practical generation interval-based approach to inferring the strength of epidemics from their speed

, 2018
Infectious-disease outbreaks are often characterized by the reproductive number and 𝓡 exponential rate of growth r. 𝓡 provides information about out-break control and predicted final size.
David Champredon, Sang Woo Park, Joshua S. Weitz, Jonathan Dushoff   +3 more
core   +1 more source

Common misspecification of the generation interval leads to reproduction number underestimation in phylodynamic inference

Epidemics
Generation intervals are distributions that describe the time between infection and onward transmission. They are a key epidemiological quantity because, together with the reproduction number R, they determine the population-level growth rate r of a ...
Yeongseon Park, Katia Koelle
doaj   +1 more source

Establishing an assay to evaluate d‐amino acid oxidase enzyme kinetics and inhibition using WST‐8 redox dye

FEBS Open Bio, EarlyView.
This study investigated a novel WST‐8‐based assay for evaluating d‐Amino acid oxidase (DAO) inhibitors. We confirmed its effectiveness using known inhibitors and found that uremic toxins possess relatively weak inhibitory activity compared to existing drugs.
Kahoko Miyake, Yuki Enoki, Yuka Nakazawa, Kazuaki Taguchi, Kazuaki Matsumoto   +4 more
wiley   +1 more source

Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system

FEBS Open Bio, EarlyView.
An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková, Veronika Hovanová, Jiri Damborsky, Erik Sedlák   +3 more
wiley   +1 more source

Predictors for interval appendectomy in non-operatively treated complicated appendicitis

, 2019
Purpose: To determine the incidence rate and identify predictive factors for interval appendectomy after non-operatively treated complicated appendicitis.
van Rossem, C. C., Bemelman, W. A., Musters, G. D., van Geloven, A. A. W., de Jonge, J., Bolmers, M. D. M.   +5 more
core   +1 more source

Prediction of Blast Furnace Gas Generation Based on Bayesian Network

Energies
Due to the large fluctuation of blast furnace gas (BFG) generation and its complex production characteristics, it is difficult to accurately obtain its gas change rules.
Zitao Wu, Dinghui Wu
doaj   +1 more source