Results 121 to 130 of about 495,921 (307)

Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma

Molecular Oncology, EarlyView.
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski, Júlia Perera‐Bel, Alejo Rodriguez‐Vida, Nuria Juanpere, Jihyun Lee, Daniel E. Michaud, Jennifer L. Guerriero, Kent W. Mouw, Aristotelis Bamias, Filipe L. F. Carvalho, Joaquim Bellmunt   +10 more
wiley   +1 more source

N-K Constrained Composite Generation and Transmission Expansion Planning With Interval Load

IEEE Access, 2017
The uncertainties of the predicted load demand and N-K contingencies are very significant aspects to composite generation and transmission expansion planning (CGTEP).
Shaoyun Hong, Haozhong Cheng, Pingliang Zeng   +2 more
doaj   +1 more source

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

Molecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington, Divya L. Dayanidhi, Mohammad Zokaasadi, John B. Mantyh, Pelumi D. Olawuni, Gabrielle Rupprecht, Jeremy M. Force, Shannon McCall, Ashwani K. Bahl, David S. Hsu, Jason A. Somarelli   +10 more
wiley   +1 more source

Changing case order to optimise patterns of performance in mammography screening (CO-OPS) : study protocol for a randomized controlled trial [PDF]

, 2014
Background: X-ray mammography remains the predominant test for screening for breast cancer, with the aim of reducing breast cancer mortality. In the English NHS Breast Screening Programme each woman’s mammograms are examined separately by two expert ...
Parsons, Helen, Campbell, H, Clarke, A, Dunn, Janet, Campbell, H., Dunn, J, Stallard, Nigel, Nigel Stallard, Gates, S, Wallis, Matthew G., Stallard, N, Szczepura, A, Sian Taylor-Phillips, Aileen Clarke, Sellars, S, Szczepura, Ala; id_orcid, Szczepura, Ala, Parsons, H., Stallard, N., Taylor-Phillips, S., Dunn, J., Campbell, Helen, Sellars, Sarah, Gates, Simon, Parsons, H, Helen Campbell, Dunn, Janet A., Stellars, S., Matthew G Wallis, Gates, S., Ala Szczepura, Sarah Sellars, Simon Gates, Wallis, M. G., Wallis, MG, Wallis, Matthew G, Taylor-Phillips, S, Helen Parsons, Taylor-Phillips, Sian, Clarke, Aileen, Janet Dunn, Clarke, A.   +41 more
core   +1 more source

Steady-State Interval Detection and Nonlinear Modeling for Automatic Generation Control Systems

IEEE Access, 2019
Automatic generation control systems are designed to adjust electric power outputs of multiple generators simultaneously in accordance with the current load.
Pengfei Cao, Jiandong Wang, Chao Zhang
doaj   +1 more source

Estimating the generation interval from the incidence rate, the optimal quarantine duration and the efficiency of fast switching periodic protocols for COVID-19. [PDF]

Sci Rep, 2022
Lippiello E, Petrillo G, de Arcangelis L.   +2 more
europepmc   +1 more source

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

Molecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi, Mandy Berndt‐Paetz, Eileen Lerner, Gregoire Najjar, Anca Azoitei, Krishna Pal Singh, Shailendra Kumar Gupta, Olaf Wolkenhauer, Cagatay Günes, Otmar Huber, Marc‐Oliver Grimm, Daniel Steinbach   +11 more
wiley   +1 more source

Template generation for continuous transfer functions using interval analysis

, 2000
This paper presents a template generation algorithm for transfer functions that are continuous in the uncertain system parameters. The algorithm is developed using interval mathematics.
NATARAJ, PSV, SARDAR, GAUTAM
core   +1 more source

Renewable Generation (Wind/Solar) and Load Modeling through Modified Fuzzy Prediction Interval

International Journal of Photoenergy, 2018
The accuracy of energy management system for renewable microgrid, either grid-connected or isolated, is heavily dependent on the forecasting precision such as wind, solar, and load.
Syed Furqan Rafique, Zhang Jianhua, Rizwan Rafique, Jing Guo, Irfan Jamil   +4 more
doaj   +1 more source

Estimating the generation interval and inferring the latent period of COVID-19 from the contact tracing data. [PDF]

Epidemics, 2021
Zhao S, Tang B, Musa SS, Ma S, Zhang J, Zeng M, Yun Q, Guo W, Zheng Y, Yang Z, Peng Z, Chong MK, Javanbakht M, He D, Wang MH.   +14 more
europepmc   +1 more source