Results 171 to 180 of about 10,994,854 (357)

Is Generation X the new Civic Generation? An exploratory analysis of social capital, environmental attitudes and behaviours in an Australian community

open access: yes, 2004
This study investigated generational differences and similarities in social capital, environmental attitudes and behaviours in an affluent Australian community, comparing the Civic Generation (60 years+) with the independent youth of today, the ...
Buys, Laurie, Miller, Evonne
core  

Circulating tumor cell viability during and after radiotherapy mirrors treatment response in cancer patients

open access: yesMolecular Oncology, EarlyView.
Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy   +10 more
wiley   +1 more source

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

open access: yesMolecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel   +12 more
wiley   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

open access: yesMolecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura   +19 more
wiley   +1 more source

The contemporary field training program: generation X training generation Y [PDF]

open access: yes, 2013
Discusses the issues that occur when generation X trainers teach generation Y recruits ...
Carlisle, Rebecca
core  

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

open access: yesMolecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis   +3 more
wiley   +1 more source

Generation or culture? Work attitude drivers: An analysis in Latin America and Iberian countries [PDF]

open access: yes
This paper concerns the work attitude drivers within the current scenario taking into account two different factors of influence, the culture and the generation of each individual. To belong to a given generation can affects individuals work attitudes as
Gallifa, Angela   +2 more
core  

Flow Enabled Target Capture Halbach‐based magnetic enrichment increases circulating tumor cell capture from blood in metastatic cancer patients

open access: yesMolecular Oncology, EarlyView.
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens   +6 more
wiley   +1 more source

EFL Teachers’ (Generation X and Y) and Learners’ (Generation Z) Perceptions On 21st Century Skills

open access: yese-Kafkas Eğitim Araştırmaları Dergisi
This quantitative study intended to reveal the perceptions of Generation X and Generation Y EFL teachers and learners of Generation Z regarding their competency of and the importance they attach to the 21st century skills.
Özgür Yıldırım, Meriç Akkaya Önal
doaj  

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