Results 161 to 170 of about 10,994,854 (357)
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
Development and spatio-spectral mapping of a capillary high harmonic source [PDF]
, 2008 This work describes the development and operation of a capillary based High Harmonic Generation (HHG) system. Using this system a coherent beam of soft x-rays is generated, studied and applied.
Praeger, Matthew
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Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
New social groups in modern stratification systems of global society
Социологическая наука и социальная практика, 2013 In modern developed and developing societies precarisation labor relations is extensive. This phenomenon has given rise to a new social group in the social structure of modern societies, called prekariat.
Zinaida T. Golenkova +1 more
doaj
, 1997 This special issues section of JPAE provides an opportunity to address the experience of the new generation of MPA students who are often labeled the X Generation.
Marshall, Gary S.
core
Molecular Oncology, EarlyView.Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source
GPS-Based Precision Baseline Reconstruction for the TanDEM-X SAR-Formation
, 2007 The TanDEM-X formation employs two separate spacecraft to collect interferometric Synthetic Aperature Radar (SAR) measurements over baselines of about 1 km.
van Barneveld, Luuk +3 more
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Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
MARKETING COMMUNICATION TO GENERATION X [PDF]
, 2007 Generace X z margetingového hlediska. Proč je Generace X důležitá pro marketing. Jaké je její nákupní chování, jak se tato skupina populace dá zadefinovat a uchopit jako tržní segment. Co jí formovalo a proč je specifická.Marketing to Generation X.
Sabová, Michaela
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Molecular Oncology, EarlyView.Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata +10 more
wiley +1 more source