Results 261 to 270 of about 10,994,854 (357)

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

FEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo, Sandy Richter, Christoph Bach, Wieland Kiess, Anna Kirstein, Diana Le Duc, Antje Garten   +6 more
wiley   +1 more source

The vegetal model: Buffon's general theory of reproduction. [PDF]

Hist Philos Life Sci
Sandford S.
europepmc   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Environmental Sustainability in Dialysis Units: A Scoping and Integrative Review of Challenges and Innovations in Nephrology. [PDF]

Healthcare (Basel)
Mata-Lima A, Paquete AR, Mata-Lima H.
europepmc   +1 more source

Effect of terahertz irradiation on DNA damage repair in living cells

FEBS Open Bio, EarlyView.
We investigated the effect of terahertz (THz) wave irradiation on DNA double‐strand break (DSB) repair in living cells. We found that THz irradiation enhanced DSB repair at specific frequencies, whereas heat treatment inhibited it, indicating that this effect is nonthermal and frequency‐specific.
Yuya Ueno, Shota Yamazaki, Hiromichi Hoshina, Masahiko Harata   +3 more
wiley   +1 more source

Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance

Aging and Cancer, EarlyView.
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang, Zhong Fan, Runmeng Liu, Xiaotian Zhang   +3 more
wiley   +1 more source

Elevated depression and anxiety symptoms among younger adults in Germany during the post-pandemic period. [PDF]

BMC Public Health
Lena P, Emily S, Jasmin H, Franziska KD, M FJ, Jonas F.   +5 more
europepmc   +1 more source

5G/6G Networks for Wireless Communication and IoT. [PDF]

Sensors (Basel)
Suraci C, Araniti G.
europepmc   +1 more source

Maximizing the Value of Learning Assistants for Students' Belonging, Mattering, and Confidence in Gateway STEM Courses. [PDF]

CBE Life Sci Educ
Zepeda CD, Rosemond SN, Johnson HJ, Clements TP, Albarran M, Lee G, Watson M, Brame CJ.   +7 more
europepmc   +1 more source

Fully synthetic replication of complex real biological cell clusters using a novel cluster-based 'Rosetta-Routine' computational modelling process. [PDF]

PLoS Comput Biol
Mason B, Justham L, Whitby L, Whitby A, Scott S, Nti S, Petzing J.   +6 more
europepmc   +1 more source