Results 121 to 130 of about 24,622,115 (294)

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Silica microfibres for broadband third harmonic generation

open access: yes
We report broadband third harmonic generation via intermodal phase matching in silica microfibres of several centimetres. A 5 dB conversion bandwidth exceeding 36 nm was recorded, with harmonic power detected over a 150 nm ...
Ding, M.   +5 more
core   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

Coping with Generation Y in schools [PDF]

open access: yes, 2009
In recent times, complaining about the Y Generation and its perceived lack of work ethic has become standard dinner-party conversation amongst Baby Boomers. Discussions in the popular press (Salt, 2008) and amongst some social commentators (Levy, Carroll,
Carstensen, Linda, Smeed, Judy L.
core  

Intergenerational World: Generation Y’s Perspective on Agedness

open access: yesSenectus
Birinci, E. (2020). Y kuşağının yaşlı ve yaşlılık algısı. Gazi Kitabevi, 274 s.
Ayşe Bahar Duyar Akça
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

The Relationship Between Social Media Addiction and Narcissism on Social Media: A Comparison Between Generations Y and Z

open access: yesYeni Medya
One of the most effective outcomes of social media addiction and narcissistic tendencies is the failure observed in interpersonal relationships. From this perspective, social media addiction and narcissism are not only individual issues but also ...
Hatice Budak, Mehmet Harmancı
doaj   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Prestige y 11-M : la vertebración política de la gestión de catástrofes [PDF]

open access: yes, 2007
Between 2002 and 2004 Spain was jolted by two big crisis scenarios with a very different nature but two common characteristics. On one hand, they required an immediate response of some magnitude and complex management. On the other, they both caused a
García Sánchez, Esther   +3 more
core  

Maybe More Than Mates, Maybe Not? The Modern Meaning of a Modern Alliance

open access: yes, 2022
Article in Next-generation perspectives on the US–Australia alliance (Next Generation Perspectives Policy Paper; August 2022)Benjamin Cherry-Smith, Renee Cremer, Monique Currie and Jena ...
Cremer, R.   +3 more
core  

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