Results 101 to 110 of about 1,106,397 (257)
ABSTRACT Background Chronic micro‐inflammation in patients with end‐stage renal disease (ESRD) is a significant driver of cardiovascular complications and diminished quality of life. While standard hemodialysis (SHD) effectively manages small‐molecule clearance, its ability to remove medium‐to‐large uremic toxins—the primary catalysts of systemic ...
Hongwei Zuo +5 more
wiley +1 more source
Modern continuous-time generative models typically induce \emph{V-shaped} flows: each sample travels independently along a nearly straight trajectory from the prior to the data. Although effective, this independent movement overlooks the hierarchical structures that exist in real-world data. To address this, we introduce \emph{Y-shaped generative flows}
Arip Asadulaev +5 more
openaire +2 more sources
ABSTRACT Background Japan has one of the highest dialysis prevalence rates worldwide and a shrinking, aging population. Whether dialysis burden has entered a sustained post‐peak phase or whether recent declines partly reflect pandemic‐related disruptions remains uncertain.
Hatice Şahin +2 more
wiley +1 more source
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi +5 more
wiley +1 more source
Intergenerational World: Generation Y’s Perspective on Agedness
Birinci, E. (2020). Y kuşağının yaşlı ve yaşlılık algısı. Gazi Kitabevi, 274 s.
Ayşe Bahar Duyar Akça
doaj +1 more source
Administración Industrial y General
La racionalización del gobierno de la empresa es punto esencial de la doctrina del ingeniero francés Henri Fayol, universalmente conocida bajo el nombre de fayolismo. El tiempo transcurrido desde la primera publicación de su obra «Administración industrial y general» no le ha restado un ápice de su actualidad, que permanece hoy en día con el clasicismo
openaire +2 more sources
Organoids in pediatric cancer research
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
One of the most effective outcomes of social media addiction and narcissistic tendencies is the failure observed in interpersonal relationships. From this perspective, social media addiction and narcissism are not only individual issues but also ...
Hatice Budak, Mehmet Harmancı
doaj +1 more source
Reciprocal control of viral infection and phosphoinositide dynamics
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source

