Results 91 to 100 of about 2,042,710 (299)
By dawn or dusk—how circadian timing rewrites bacterial infection outcomes
FEBS Letters, EarlyView.The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo +2 more
wiley +1 more source
Hematopoietic (stem) cells—The elixir of life?
FEBS Letters, EarlyView.The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo +4 more
wiley +1 more source
Can new generations explain neutrino masses? [PDF]
, 2011 In this talk we explore the possibility that the smallness of the observed neutrino masses is naturally understood in a modified version of the standard model with N extra generations of fermions and N right-handed neutrinos, in which light neutrino ...
Aparici, A. +3 more
core +1 more source
Four Generations, Higgs Physics, and the MSSM
, 2010 We consider the effects of a fourth generation of chiral fermions within the MSSM. Such a model offers the possibility of having the lightest neutral Higgs boson significantly heavier than in the three generation MSSM.
Dawson, S., Jaiswal, P.
core +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Nations, Overlapping Generations and Historic Injustice [PDF]
, 2006 This article considers the question of the responsibility that present day generations bear as a result of the actions of their ancestors. Is it morally significant that we share a national identity with those responsible for the perpetration of historic
Butt, Daniel
core
FEBS Letters, EarlyView.Bifidobacterium bifidum establishes symbiosis with infants by metabolizing lacto‐N‐biose I (LNB) from human milk oligosaccharides (HMOs). The extracellular multidomain enzyme LnbB drives this process, releasing LNB via its catalytic glycoside hydrolase family 20 (GH20) lacto‐N‐biosidase domain.
Xinzhe Zhang +5 more
wiley +1 more source
QUASILINEAR, OVERLAPPING-GENERATIONS ECONOMIES [PDF]
The quasilinearity assumption (informally speaking, the assumption that utility is linear in the numeraire good, or that income effects are absent from the demand of nonnumeraire goods) makes surplus analysis exact in economies where all agents are ...
Joaquim Silvestre
core
How Different Generations Perceive Political News [PDF]
, 2018 The 2016 presidential election was one of the first elections to see new media play a large role. While also being the first presidential election many millennials could vote in, this research paper looks at how different generations used various news ...
Hilfrank, Elizabeth C.
core +1 more source
Molecular bases of circadian magnesium rhythms across eukaryotes
FEBS Letters, EarlyView.Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley +1 more source