Results 61 to 70 of about 2,042,710 (299)

Pathogenic Germline PALB2 and RAD50 Variants in Patients With Relapsed Ewing Sarcoma

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Approximately 10% of patients with Ewing sarcoma (EwS) have pathogenic germline variants. Here, we report two cases: first, a novel germline pathogenic variant in partner and localizer of BRCA2 (PALB2) in a patient with a late EwS relapse. Its impact on homologous recombination is demonstrated, and breast cancer risk is discussed.
Molly Mack   +12 more
wiley   +1 more source

The Motivation Problem, Future Generations, and the Idea of “Leaving the Earth No Worse” [PDF]

open access: yes, 2019
The author examines the problem of motivation about future generations. He argues that though many philosophers think that direct motivations are problematic for future generations only, they are not unproblematic for the current generations too, and ...
Huda, Kazi A. S. M. Nurul
core  

Standard Model Extension with Flipped Generations

open access: yes, 2018
An extension of the Standard Model is presented that leads to the possible existence of new gauge bosons with masses in the range of a few TeV. Due to the fact that their couplings to Standard Model fermions are strongly suppressed, it is possible for ...
Alvarado, Carlos, Aranda, Alfredo
core   +1 more source

Improved Outcomes for Older Children, Adolescents, and Young Adults With Neuroblastoma in the Post‐Immunotherapy Era: An Updated Report From the International Neuroblastoma Risk Group

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background We describe clinical and biologic characteristics of neuroblastoma in older children, adolescents, and young adults (OCAYA); describe survival outcomes in the post‐immunotherapy era; and identify if there is an age cut‐off that best discriminates outcomes.
Rebecca J. Deyell   +14 more
wiley   +1 more source

Quaternionic Mass Matrices and CP Symmetry [PDF]

open access: yes, 1997
A viable formulation of gauge theory with extra generations in terms of quaternionic fields is presented. For the theory to be acceptable, the number of generations should be equal to or greater than 4. The quark-lepton mass matrices are generalized into
Lim, C. S.
core   +2 more sources

GENERALIZED SPACES OF GENERAL RELATIVITY [PDF]

open access: yesProceedings of the National Academy of Sciences, 1959
1. This paper is a revision of the paper with the same title which was published a year ago. The paper deals with a space of four dimensions V4 of coordinates xi as i takes the values 1 to 4. The geometry of the space is based upon the asymmetric functions gij and the asymmetric coefficients of connection Prk and upon the Einsteinm equation2 gij,k ...
openaire   +2 more sources

Patient‐Level Barriers and Facilitators to Inpatient Physical Therapy in Adolescents and Young Adults With a Hematological Malignancy: A Qualitative Study

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Despite their increased risk for functional impairment resulting from cancer and its treatments, few adolescents and young adults (AYAs) with a hematological malignancy receive the recommended or therapeutic dose of exercise per week during inpatient hospitalizations.
Jennifer A. Kelleher   +8 more
wiley   +1 more source

Resident-Guided Case Discussions in Reproductive Endocrinology & Infertility

open access: yesMedEdPORTAL, 2012
This resource is a series of resident-guided case discussions in reproductive endocrinology and infertility. It is designed to be an adjunctive curriculum tool to allow trainees in gynecology to improve their comfort with core concepts in reproductive ...
Brenda Houmard   +2 more
doaj   +1 more source

Psychological Safety Among Interprofessional Pediatric Oncology Teams in Germany: A Nationwide Survey

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Psychological safety (PS) is essential for teamwork, communication, and patient safety in complex healthcare environments. In pediatric oncology, interprofessional collaboration occurs under high emotional and organizational demands. Low PS may increase stress, burnout, and adverse events.
Alexandros Rahn   +4 more
wiley   +1 more source

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