Results 41 to 50 of about 331,887 (241)

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

Influence of AI literacy and 21st-century skills on the acceptance of generative artificial intelligence among college students

Frontiers in Education
IntroductionFostering Artificial Intelligence (AI) literacy and equipping college students with 21st-century skills in the generative AI era have become a global educational priority. In this context, generative AI offers opportunities for development in
Reham Salhab, Mosab M. Aboushi
doaj   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Connecting dreams with visual brainstorming instruction

Visual Intelligence
Recent breakthroughs in understanding the human brain have revealed its impressive ability to efficiently process and interpret human thoughts, opening up the possibility of intervening in brain signals. In this paper, we aim to develop a straightforward
Yasheng Sun, Bohan Li, Mingchen Zhuge, Deng-Ping Fan, Salman Khan, Fahad Shahbaz Khan, Hideki Koike   +6 more
doaj   +1 more source

Telaah Metode Pembelajaran Perancangan: Eksplorasi Desain Instalasi dengan Penerapan Generative AI

Arsitekno
Pelibatan generative AI ke dalam proses merancang arsitektur sudah banyak dilakukan. Berbagai studi juga telah dilakukan untuk menelaah penerapan generative AI di dalam proses pembelajaran arsitektur namun dalam konteks Indonesia belum banyak dipaparkan
Adriyan Kusuma
doaj   +1 more source

SIRT4 positively regulates autophagy via ULK1, but independently of HDAC6 and OPA1

FEBS Open Bio, EarlyView.
Cells expressing SIRT4 (H161Y), a catalytically inactive mutant of the sirtuin SIRT4, fail to upregulate LC3B‐II and exhibit a reduced autophagic flux under stress conditions. Interestingly, SIRT4(H161Y) promotes phosphorylation of ULK1 at S638 and S758 that are associated with inhibition of autophagy initiation.
Isabell Lehmkuhl, Khawar Amin, Lydia Gabriel, Nils Hampel, Afshin Iram, Julia Hesse, Constanze Wiek, Jasmin Thuy Vy Nguyen, Helmut Hanenberg, Jürgen Scheller, M. Reza Ahmadian, Björn Stork, Doreen M. Floss, Roland P. Piekorz   +13 more
wiley   +1 more source

Generative Artificial Intelligence in Education: Advancing Adaptive and Personalized Learning

Acta Informatica Pragensia
The integration of generative artificial intelligence (AI) into adaptive and personalized learning represents a transformative shift in the educational landscape.
Manel Guettala, Samir Bourekkache, Okba Kazar, Saad Harous   +3 more
doaj   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

Effects of generative artificial intelligence on cognitive effort and task performance: study protocol for a randomized controlled experiment among college students

Trials
Background The advancement of generative artificial intelligence (AI) has shown great potential to enhance productivity in many cognitive tasks. However, concerns are raised that the use of generative AI may erode human cognition due to over-reliance ...
Youjie Chen, Yingying Wang, Torsten Wüstenberg, Rene F. Kizilcec, Yiwen Fan, Yanfei Li, Bin Lu, Meng Yuan, Junlai Zhang, Ziyue Zhang, Pascal Geldsetzer, Simiao Chen, Till Bärnighausen   +12 more
doaj   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source