Results 221 to 230 of about 405,858 (264)

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

FEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava, Anoop Saraya, Deepak Gunjan, Rinu Sharma   +3 more
wiley   +1 more source

Inverse Molecular Design for the Discovery of Organic Energy Transfer Photocatalysts: Bridging Global and Local Chemical Space Exploration. [PDF]

J Am Chem Soc
Schlosser L, Rendel NH, Gemen J, Glorius F, Jorner K.   +4 more
europepmc   +1 more source

Evaluation of in vitro toxicity of common phytochemicals included in weight loss supplements using 1H NMR spectroscopy

FEBS Open Bio, EarlyView.
We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies, Garth L. Maker, Ian F. Musgrave, Samantha Lodge   +3 more
wiley   +1 more source

From Latent Manifolds to Targeted Molecular Probes: An Interpretable, Kinome-Scale Generative Machine Learning Framework for Family-Based Kinase Ligand Design. [PDF]

Biomolecules
Verkhivker G, Kassab R, Krishnan K.
europepmc   +1 more source

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

FEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani, Tobias Dreyer, Meriem Naim, Rea Lo Dico, Natalia A. Ignatenko, Viktor Magdolen, Dalila Darmoul   +6 more
wiley   +1 more source

Mechanical characterization of PETG - carbon fiber composite parts using 3D printing for drone frame application. [PDF]

Sci Rep
Palaniappan M, Kumar PM, Arunkumar P, Gebreyohannes DT.   +3 more
europepmc   +1 more source

International Perspectives on Digital and Generative AI Adoption and Governance in Undergraduate Dental Education: A Cross-Sectional Survey. [PDF]

Dent J (Basel)
Olegário IC, Coffey N, Chaurasia A, Leung A.   +3 more
europepmc   +1 more source

Supporting the creative industries through the AI turn: A comparative analysis of Scottish policy and the needs of Scotland's creative practitioners. [PDF]

PLoS One
Black SR, Moruzzi C, Osborne N, Terras M, Zeller F.   +4 more
europepmc   +1 more source

Correction: Parameter-optimized generative adversarial network framework for synthetic MRI generation: fine-tuning critical variables for enhanced image fidelity. [PDF]

Front Med (Lausanne)
Arockia Selvarathinam ALXR, Anbalagan N, Srinivasu PN, Choi J, Ijaz MF.   +4 more
europepmc   +1 more source

Potential Application Value and Needs of Using Generative AI Videos for Health Management for Older Adults: Qualitative Study. [PDF]

JMIR Aging
Liu T, Luo YT, He Z, Pang P, Chan KS, Lau Y.   +5 more
europepmc   +1 more source