Results 221 to 230 of about 394,851 (262)

Cotargeting TREM2 and IL2 pathways triggers multipronged anticancer immunity

Molecular Oncology, EarlyView.
Von Locquenghien et al. report that MiTE‐144, a triggering receptor expressed on myeloid cells 2 (TREM2) blocking antibody fused to interleukin‐2 (IL2) variant with tumour microenvironment restricted activation, demonstrates superior anticancer efficiency in a preclinical setting.
Isaure Vanmeerbeek, Jenny Sprooten, Abhishek D. Garg   +2 more
wiley   +1 more source

Structured generative modelling of earthquake response spectra with hierarchical latent variables in hyperbolic geometry. [PDF]

Sci Rep
Wright A, Fayaz J.
europepmc   +1 more source

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

Molecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source

Turbo Charge Your CME and CPD Operations Using Generative AI Tools. [PDF]

J CME
Akunuru RV, Dodgson A, Milbauer DD, Perch A.   +3 more
europepmc   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

ML-automated microfluidic circuit design. [PDF]

Sci Adv
Birtek MT, Aktas V, Aktas B, Abdullah AC, Ozcan A, Tasoglu S.   +5 more
europepmc   +1 more source

Generative AI in microbial evolution and resistance: toward robust, explainable, and equitable predictions. [PDF]

Front Microbiol
Sufi F.
europepmc   +1 more source

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General Design Classifications

Journal of the American Academy of Child & Adolescent Psychiatry, 2002
This column described the general design classifications of between-groups, within-subjects, and mixed designs. Remember that in between-groups designs, each participant is in only one group or condition. In within-subjects or repeated-measures designs, on the other hand, each participant receives all the conditions or levels of the independent ...
George A, Morgan, Jeffrey A, Gliner, Robert J, Harmon   +2 more
openaire   +2 more sources