Results 111 to 120 of about 22,229,619 (357)

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

FEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo, Catherine S. Palmer, Jacqueline M. Kimmey   +2 more
wiley   +1 more source

Application of SMILES-based molecular generative model in new drug design

Frontiers in Pharmacology, 2022
Weiya Kong, Yuejuan Hu, Jiao Zhang, Qiaoyin Tan   +3 more
doaj   +1 more source

Learnable Priors Support Reconstruction in Diffuse Optical Tomography

Photonics
Diffuse Optical Tomography (DOT) is a non-invasive medical imaging technique that makes use of Near-Infrared (NIR) light to recover the spatial distribution of optical coefficients in biological tissues for diagnostic purposes.
Alessandra Serianni, Alessandro Benfenati, Paola Causin   +2 more
doaj   +1 more source

Hematopoietic (stem) cells—The elixir of life?

FEBS Letters, EarlyView.
The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo, Jonah Anderson, Emilie Dinh Vedrenne, Noël Yeh Martín, Jette Lengefeld   +4 more
wiley   +1 more source

Spatiotemporal Anomaly Detection in Distributed Acoustic Sensing Using a GraphDiffusion Model

Sensors
Distributed acoustic sensing (DAS), which can provide dense spatial and temporal measurements using optical fibers, is quickly becoming critical for large-scale infrastructure monitoring.
Seunghun Jeong, Huioon Kim, Young Ho Kim, Chang-Soo Park, Hyoyoung Jung, Hong Kook Kim   +5 more
doaj   +1 more source

Risks and countermeasures of artificial intelligence generated content technology in content security governance

Dianxin kexue, 2023
Recently, artificial intelligence generated content (AIGC) technology has achieved various disruptive results and has become a new trend in AI research and application, driving AI into a new era.Firstly, the development status of AIGC technology was ...
Zhe QIAO
doaj  

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Multi-Task Trajectory Prediction Using a Vehicle-Lane Disentangled Conditional Variational Autoencoder

Sensors
Trajectory prediction under multimodal information is critical for autonomous driving, necessitating the integration of dynamic vehicle states and static high-definition (HD) maps to model complex agent–scene interactions effectively.
Haoyang Chen, Na Li, Hangguan Shan, Eryun Liu, Zhiyu Xiang   +4 more
doaj   +1 more source

3D Conformational Generative Models for Biological Structures Using Graph Information-Embedded Relative Coordinates [PDF]

, 2022
Mingyuan Xu, Weifeng Huang, Min Xu, Jinping Lei, Hongming Chen, Jinping Lei, Hongming Chen   +6 more
openalex   +1 more source

Structural insights into lacto‐N‐biose I recognition by a family 32 carbohydrate‐binding module from Bifidobacterium bifidum

FEBS Letters, EarlyView.
Bifidobacterium bifidum establishes symbiosis with infants by metabolizing lacto‐N‐biose I (LNB) from human milk oligosaccharides (HMOs). The extracellular multidomain enzyme LnbB drives this process, releasing LNB via its catalytic glycoside hydrolase family 20 (GH20) lacto‐N‐biosidase domain.
Xinzhe Zhang, Naoki Sunagawa, Toma Kashima, Kiyohiko Igarashi, Akimasa Miyanaga, Shinya Fushinobu   +5 more
wiley   +1 more source