Results 91 to 100 of about 425,706 (317)

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

Low speed doubly salient permanent magnet generator with passive rotor for a tidal current turbine [PDF]

open access: yes, 2013
This paper presents a low speed permanent magnet generator that can be associated with a tidal turbine. This structure has a passive rotor which leads to a simple and robust structural solution. The principle of operation and an electromecanical model of
MOREAU, Luc   +3 more
core   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

GA/SA-based hybrid techniques for the scheduling of generator maintenance in power systems

open access: yes, 2000
YesProposes the application of a genetic algorithm (GA) and simulated annealing (SA) based hybrid approach for the scheduling of generator maintenance in power systems using an integer representation.
Galloway, S.J.   +3 more
core   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Development of a cantilever beam generator employing vibration energy harvesting

open access: yes, 2006
This paper details the development of a generator based upon a cantilever beam inertial mass system which harvests energy from ambient environmental vibrations. The paper compares the predicted results from Finite Element Analysis (FEA) of the mechanical
Tudor, M.J.   +4 more
core  

GENERALIZING [PDF]

open access: yesAJN, American Journal of Nursing, 1913
n ...
openaire   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Application of optimization algorithms in the design of a superconducting A.C. generator rotor [PDF]

open access: yes, 1990
The superconducting a.c. generator is expected to be the optimum choice among a.c. generation systems in future because of its reduced size, high efficiency, high terminal voltage and its contribution to the stability of the power system.
Safi, Sabah K.
core  

Implementation of supersymmetric processes in the HERWIG event generator

open access: yes, 2002
We describe the implementation of supersymmetric processes in the HERWIG Monte Carlo event generator. We define relevant parameter and mixing conventions and list the hard scattering matrix elements.
Odagiri, K.   +13 more
core   +1 more source

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