Results 61 to 70 of about 1,906,559 (257)

Decoding the dynamic extracellular matrix in cancer—3D models and bioscaffolds rewire the rules of tumor progression

open access: yesFEBS Letters, EarlyView.
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani   +3 more
wiley   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

open access: yesFEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi   +6 more
wiley   +1 more source

A Taxonomy of Small Markovian Errors

open access: yesPRX Quantum, 2022
Errors in quantum logic gates are usually modeled by quantum process matrices (CPTP maps). But process matrices can be opaque and unwieldy. We show how to transform the process matrix of a gate into an error generator that represents the same information
Robin Blume-Kohout   +6 more
doaj   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

A monolithic MQW InP/InGaAsP-based comb generator [PDF]

open access: yes, 2006
We report a monolithic optical frequency comb generator using quaternary/quaternary multiple quantum well InV/InGaAsP material as phase modulator and gain medium in a Frequency Modulated (FM) laser design. The modulation was generated by quantum confined
I. Lealman   +13 more
core   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

A Matrix State-to-Responsibility Mapping Model for Post-Contingency Corrective Dispatch in Power Systems

open access: yesMathematics
Post-contingency corrective dispatch restores a feasible AC voltage–current state, but the corrected state is usually not carried forward to responsibility allocation.
Kai-Hung Lu, Wenjun Qian, Chunhe Lv
doaj   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

open access: yesFEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt   +8 more
wiley   +1 more source

M-MATRIX-WP6.M1 - "DASHBOARDS OPERATIONAL WITHIN THE PILOT PARTICIPATING AGENCIES"

open access: yes, 2022
M-MATRIX-WP6.M1 - “Dashboards operational within the pilot participating agencies” Milestone report for M1 of MATRIX ...
MATRIX
core   +1 more source

Closed loop frequency tuning of a vibration-based micro-generator

open access: yes, 2008
This paper presents a tunable electromagnetic vibration-based micro-generator with closed loop frequency tuning. Frequency tuning is realized by applying an axial tensile force to the micro-generator.
Beeby, Steve   +3 more
core   +1 more source

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