Results 211 to 220 of about 2,343,217 (327)
Unveiling Global Diversity of Patescibacteriota and Functional Interactions with Host Microbes
Patescibacteriota represents a diverse group of ultra‐small epibiotic bacteria, which is largely overlooked. By integrating ribosomal protein S3‐based community profiling with MAG‐based metabolic potential analyses, this study provides new insights into their distribution, diversity, and potential interactions with other bacteria across diverse ...
Yanhan Ji +12 more
wiley +1 more source
Bioequivalence centres in Africa: current state and opportunities for growth. [PDF]
Ncube BM, Muthuri S, Ajose O, Kikwai L.
europepmc +1 more source
This research deciphers the m6A transcriptome by profiling its sites and functional readout effects: from mRNA stability, translation to alternative splicing, across five different cell types. Machine learning model identifies novel m6A‐binding proteins DDX6 and FXR2 and novel m6A reader proteins FUBP3 and L1TD1.
Zhou Huang +11 more
wiley +1 more source
Lessons learned from implementing FAIRification workflows in diabetes research in Germany. [PDF]
Inau ET +10 more
europepmc +1 more source
Two Novel S‐methyltransferases Confer Dimethylsulfide Production in Actinomycetota
This study identifies two novel S‐adenosine‐methionine‐dependent methyltransferases, MddM1 and MddM2, in actinomycetes from the Mariana Trench. These enzymes can convert toxic hydrogen sulfide (H2S) and methanethiol (MeSH) into dimethylsulfide (DMS), serving as a cellular detoxification and oxidative stress response.
Ruihong Guo +11 more
wiley +1 more source
Fr\"oberg's Conjecture and the initial ideal of generic sequences [PDF]
Duc Trung Van
openalex
Lactylation‐Driven YTHDC1 Alleviates MASLD by Suppressing PTPN22‐Mediated Dephosphorylation of NLRP3
In MASLD, YTHDC1 undergoes increased lactylation and ubiquitination, reducing its expression. AARS1 mediates lactylation at lysine 565, while disrupted binding to LDHA further promotes lactylation, suppressing YTHDC1. This downregulation enhances PTPN22 mRNA stability, leading to NLRP3 dephosphorylation and activation, which exacerbates inflammation ...
Feng Zhang +16 more
wiley +1 more source
Response Assessment of Generic Tyrosine Kinase Inhibitors in Newly Diagnosed Chronic Myeloid Leukemia in Chronic Phase: A Prospective Study from a Tertiary Care Centre in North Eastern India. [PDF]
Choudhuri A +4 more
europepmc +1 more source

