Results 281 to 290 of about 1,135,224 (358)

PhosSight: A Unified Deep Learning Framework Boosting and Accelerating Phosphoproteome Identification to Enable Biological Discoveries

Advanced Science, EarlyView.
PhosSight is a unified deep‐learning framework for phosphoproteome identification, featured by a phosphorylation‐aware detectability predictor. It improves identification sensitivity in DDA through deep re‐localization and rescoring, accelerates DIA searches by detectability‐guided spectral library pruning, and expands phosphoproteome coverage to ...
Ben Wang, Zhiyuan Cheng, Chengying She, Hongwei Zhao, Jiahui Zhang, Lin Lv, Zhihao Yan, Hongwen Zhu, Lizhuang Liu, Yan Fu, Xinpei Yi   +10 more
wiley   +1 more source

Non-Hermitian quantum state discrimination and information flow. [PDF]

Sci Rep
Dong Q, Liu Z, Zheng C.
europepmc   +1 more source

SuFEx‐Enabled Reprogramming of Flavonoids for Selective α‐Glucosidase Covalent Inhibition

Advanced Science, EarlyView.
Selective inhibition of intestinal α‐glucosidase remains limited by poor enzyme specificity and off‐target metabolic effects. Here, SuFEx click chemistry is used to reprogram natural flavonoids into covalent inhibitors with enhanced α‐glucosidase selectivity and controlled reactivity. This strategy enables effective regulation of carbohydrate digestion
Fengyu Guo, Liwei Zhang, Minlong Wang, Yanjin Du, Tianyu Zhang, Hao Chen, Jiazeng Sun, Yang Yu, Zude He, Jie An, Xiaoxu Zhang, Weilin Lin, Fazheng Ren, Pengjie Wang, Ping Liu   +14 more
wiley   +1 more source

Effect of Pharmacist-Led Educational Intervention on Switching to Generic Medicine Among Patients Using Brand-Name Medicines in Japan. [PDF]

Pharmacy (Basel)
Tairabune T, Goto T, Yamazaki K, Kudo K, Sako KI, Maeda T, Chiba T.   +6 more
europepmc   +1 more source

Low opinion of generic oral anticancer drugs: an unacknowledged factor resulting in medication waste in China. [PDF]

Oncologist
Wang Y, Song H, Cao J, Chen Z, Xu F.
europepmc   +1 more source

The impact of the consistency evaluation policy of generic drugs on the integration of innovation chain and industrial chain in the pharmaceutical manufacturing industry. [PDF]

Front Public Health
Xie Y, Zhang W.
europepmc   +1 more source

Accelerating Generic Long-Acting Antiretrovirals for Global HIV Treatment: Workshop Findings and a Roadmap to Access. [PDF]

Clin Pharmacol Ther
Arshad U, Gaayeb L, Pertinez H, Rajoli RKR, Watkins M, Nimbolkar P, Perazzolo S, Pagi B, Wensing A, Khoo S, Boffito M, Holm R, Panos Z, Mahaka I, Venter F, Kottiri B, Crawford KW, Ho RJY, Clayden P, Domanico P, Struble K, Owen A, Flexner C.   +22 more
europepmc   +1 more source

Quadratic Subproduct Systems, Free Products, and Their C*-Algebras. [PDF]

Integr Equ Oper Theory
Arici F, Ge Y.
europepmc   +1 more source

Response to LTE "Bridging the Gap Between Patient Experience and System-Level Review: A Call for Discipline-Specific Communication in Hospital-to-Home Transitions. [PDF]

Health Expect
van Grootel J, Collet R, Major M, Wiertsema S, van Dongen J, van der Leeden M, Geleijn E, Ostelo R, van der Schaaf M.   +8 more
europepmc   +1 more source

Correction to: Evaluating the accuracy of population-specific versus generic stature estimation regression equations in a South African sample. [PDF]

Int J Legal Med
Bidmos M, Brits D.
europepmc   +1 more source