Results 221 to 230 of about 280,132 (308)

The concept of: Generic drugs and patented drugs Vs brand name drugs and non-proprietary (generic) name drugs.

Frontiers in Pharmacology, 2013
Karan eThakkar, Gauri eBilla
doaj   +1 more source

Time to Marketing of Generic Drugs After Patent Expiration in Canada.

JAMA Netw Open, 2021
Lexchin J.
europepmc   +1 more source

Reasons for the Underutilization of Generic Drugs by US Ophthalmologists: A Survey. [PDF]

Ophthalmol Ther, 2020
Dietze J, Priluck A, High R, Havens S.
europepmc   +1 more source

Small vesicles, big potential: A review of innovative exosome delivery and molecular mechanisms in preclinical myocardial infarction models

Animal Models and Experimental Medicine, EarlyView.
This narrative review discusses animal models of exosome‐based myocardial infarction treatments. Emerging techniques aim to improve exosome stability, targeting, and bioavailability for MI treatment as drug delivery vehicles and regenerative mediators that promote myocardial regeneration. Abstract Exosomes have emerged as promising therapeutic carriers,
Chayanisa Phutiyothin, Kovit Pattanapanyasat, Sarawut Kumphune   +2 more
wiley   +1 more source

A Revised Model for Muscarine Biosynthesis Involving Lysine Trimethylation

Angewandte Chemie, EarlyView.
The fatal mushroom toxin l‐(+)‐muscarine is one of the most prominent natural products. We elucidated its biosynthetic origin in the sweating mushroom Collybia rivulosa based on incorporation of stable isotope‐labeled compounds and extensive mass spectrometric analyses.
Sebastian Dörner, Kai Rogge, Felix Trottmann, Christian Hertweck, Dirk Hoffmeister   +4 more
wiley   +2 more sources

Chronic alcohol consumption compromises gut barrier integrity and promotes endotoxemia: Implications for sepsis susceptibility in immunocompromised hosts

Animal Models and Experimental Medicine, EarlyView.
Chronic alcohol exposure disrupts intestinal barrier integrity, resulting in a leaky gut and enhanced translocation of lipopolysaccharide (LPS) and microbial products into the systemic circulation. Alcohol‐induced endotoxemia drives exaggerated pro‐inflammatory responses, mitochondrial damage, and activation of the cGAS–STING pathway, particularly in ...
Thansita Bhunyakarnjanarat, Chatsuree Suksamai, Dhammika Leshan Wannigama, Kent Doi, Wiwat Chancharoenthana, Asada Leelahavanichkul   +5 more
wiley   +1 more source

Clinical Utilization of Generic Drugs and Biosimilars for Ulcerative Colitis Treatment: Insights from a Nationwide Database Study in Japan. [PDF]

Inflamm Intest Dis
Moroi R, Kakuta Y, Nagai H, Shimoyama Y, Naito T, Shiga H, Kinouchi Y, Masamune A.   +7 more
europepmc   +1 more source

Current Scientific Considerations to Verify Physiologically‐Based Pharmacokinetic Models and Their Implications for Locally Acting Products

CPT: Pharmacometrics & Systems Pharmacology, 2019
Liang Zhao, Paul Seo, Robert Lionberger
doaj   +1 more source

Blockchain Adoption for Generic Drugs in the Medicine Supply Chain with Consumers' Risk-Aversion: A Game-Theoretic Model Within Chinese Legal Framework. [PDF]

Risk Manag Healthc Policy
Cui Z, Liu X, Feng Z, Huang Z.
europepmc   +1 more source

The Burden on Society from Eleventh-Hour Citizen Petitions Filed to Slow Generic Drugs [PDF]

, 2020
Robin, Feldman
core   +1 more source