Results 81 to 90 of about 276,945 (256)
\u3ci\u3eMutual Pharmaceutical Co. v. Bartlett\u3c/i\u3e and Its Implications [PDF]
, 2013 The authors state that the U.S. Supreme Court’s preemption ruling in Mutual Pharmaceutical Co. v. Bartlett, which generally shields generic drug manufacturers from state-law damages liability for design-defect claims, may also have broader implications ...
King, Anne, Wolfman, Brian
core +1 more source
Advanced Science, EarlyView.ABSTRACT The intricate interplay between chronic psychological stress and periodontitis, mediated by oral microbiota and macrophage polarization, remains largely enigmatic. Here, we demonstrate that chronic restraint stress (CRS) exacerbates periodontitis by inducing oral microbial dysbiosis and a consequential shift in host metabolism.
Shihong Luo +13 more
wiley +1 more source
Drug Repurposing of Generic Drugs: Challenges and the Potential Role for Government. [PDF]
Appl Health Econ Health Policy, 2023 van der Pol KH +6 more
europepmc +1 more source
Multi‐Targeting Non‐Specific Genome Engineering in Bacteria
Advanced Science, EarlyView.In this study, we provide the first case to use the multi‐targeting integrase (MTI) systems in bacteria and develop a host‐independent generalizable approach, MNGE (Multi‐targeting Non‐specific Genome Engineering), for multi‐copy and random integration of metabolic genes or pathways in both Gram‐positive and Gram‐negative bacteria, which will ...
Runze Sun +7 more
wiley +1 more source
The Impact of Differential Cost Sharing of Non-Steroidal Anti-Inflammatory Agents on the Use and Costs of Analgesic Drugs [PDF]
OBJECTIVE: To estimate the effect of differential cost sharing (DCS) schemes for non-steroidal anti-inflammatory drugs (NSAIDs) on drug subsidy program and beneficiary expenditures.
Adrian R. Levy +5 more
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Advanced Science, EarlyView.In wild‐type cells, FIPV infection recruits CLTC to nsp3, facilitates DMV biogenesis and block autophagic flux to promote viral replication. CLTC knockout impairs autophagosome nucleation by reducing Beclin1–ATG14 complex expression. This disrupts the formation of autophagic precursor membranes, thereby preventing their hijacking by nsp3 for DMV ...
Juan Xu +9 more
wiley +1 more source
"Napsterizing" Pharmaceuticals: Access, Innovation, and Consumer Welfare [PDF]
We analyze the effects on consumers of an extreme policy experiment -- Napsterizing' pharmaceuticals -- whereby all patent rights on branded prescription drugs are eliminated for both existing and future prescription drugs without compensation to the ...
Edward A. Snyder +2 more
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Leveraging Artificial Intelligence and Large Language Models for Cancer Immunotherapy
Advanced Science, EarlyView.Cancer immunotherapy faces challenges in predicting treatment responses and understanding resistance mechanisms. Artificial intelligence (AI) and machine learning (ML) offer powerful solutions for cancer immunotherapy in patient stratification, biomarker discovery, treatment strategy optimization, and foundation model development.
Xinchao Wu +4 more
wiley +1 more source
Physicians' perceptions of generic drugs in China. [PDF]
Health Policy Open, 2022 He JH, Shang DW, Wang ZZ, Li XF, Wen YG.
europepmc +1 more source
Ketersediaan dan Peresepan Obat Generik dan Obat Esensial di Fasilitas Pelayanan Kefarmasian di 10 Kabupaten/kota di Indonesia [PDF]
, 2010 Background: The Ministry of Health has a special guidance for increasing the utilization of generic drugs in governmental health facilities. Beside, The Ministry of Health also has regulation for writing a generic drugs prescription at governmental ...
Handayani, R. S. (Rini) +3 more
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