Results 81 to 90 of about 2,104,479 (293)

Generic Directed Acyclic Graphs

, 2007
Generic algorithms are algorithms using abstract data types. Multiple generic algorithms can be linked together in a directed acyclic graph (generic DAG) so that more complex generic algorithms can be formed.
Gordon Novak, Generic Dags Tze, Supervisor Prof, Tze Meng Low   +3 more
core  

Computational solution to automatically map metabolite libraries in the context of genome scale metabolic networks

Frontiers in Molecular Biosciences, 2016
This article describes a generic programmatic method for mapping chemical compound libraries on organism-specific metabolic networks from various databases (KEGG, BioCyc) and flat file formats (SBML and Matlab files).
Benjamin eMerlet, Nils ePaulhe, Florence eVinson, Clément eFrainay, Maxime eChazalviel, Nathalie ePoupin, Yoann eGloaguen, Franck eGiacomoni, Fabien eJourdan   +8 more
doaj   +1 more source

Gestational Hypoxia Disrupts Medial Ganglionic Eminence Progenitor Dynamics and Interneuron Development in Schizophrenia

Advanced Science, EarlyView.
FES‐derived MGE spheroids exhibit progenitor‐stage alterations in developmental trajectory and hypoxia‐responsive transcriptional programs, followed by functional disruption. Gestational hypoxia recapitulates impaired progenitor proliferation, shortened cell‐cycle progression, interneuron developmental abnormalities, and schizophrenia‐like behaviors in
Peiyan Ni, Qiancheng Zhang, Youhui Jiang, Huiying Yao, Chuqing Zhou, Xiaoyi Tian, Shiyingnan Gao, Jun Zhao, Xinyi Ren, Naxin Xu, Mengshan Fu, Liansheng Zhao, Xueyu Qi, Xueli Yu, Wanjun Guo, Sangmi Chung, Fan Guo, Tao Li   +17 more
wiley   +1 more source

Biochemically Constrained Multi‐Omics Integration Reveals Protein–Metabolite Dependencies Across Diseases

Advanced Science, EarlyView.
ProMetNet introduces a biologically constrained deep learning framework for proteo‐metabolomic integration by embedding Reactome‐derived pathway topology into neural networks. It captures non‐linear molecular dependencies and pathway‐level metabolic reorganization, enabling interpretable discrimination.
Minghui Zhao, Na Zhou, Ruotong Liu, Xiaofei Li, Jian Li, Fuzhong Xue, Qingzhen Hou   +6 more
wiley   +1 more source

The Landscape of Long Non‐Coding RNAs Provides Insights Into the Domestication and Improvement of Pear Fruit

Advanced Science, EarlyView.
This study reveals that long non‐coding RNAs represent important regulatory components underlying pear domestication and improvement. Integrative multi‐omics analyses identify selected lncRNAs associated with fruit traits, while functional validation uncovers a lignin‐related lncRNA, lncRNA‐pys, that promotes lignin accumulation.
Bobo Song, Peilin Han, Jiaming Li, Xiaolong Li, Xiang Zhang, Jing Fan, Dongliang Liu, Jianfa Cai, Lingchao Zhang, Jun Wu   +9 more
wiley   +1 more source

The Szlenk Index and the Fixed Point Property under Renorming

Fixed Point Theory and Applications, 2010
Assume that is a Banach space such that its Szlenk index is less than or equal to the first infinite ordinal . We prove that can be renormed in such a way that with the resultant norm satisfies , where is the García-Falset coefficient ...
Benavides TDomínguez
doaj  

BioRGroup dataset: R-group expansion of ChEBI molecules referenced in the Rhea database

Scientific Data
The application of artificial intelligence in cheminformatics highlights the necessity of comprehensive datasets that fully utilize all available chemical information.
Guillaume Gricourt, Jean-Loup Faulon
doaj   +1 more source

Use of Lymphoscintigraphy Images in Nuclear Medicine to Obtain the Distribution of 99mTc Photons in Computational Exposure Models

Brazilian Journal of Radiation Sciences
This study aims to create a source catalog for Lower Limb Lymphoscintigraphy (LLL) examinations in Nuclear Medicine, using real lymphoscintigraphy images from adult male patients.
Jorge Alexandre Gomes Lins, José Wilson Vieira, Fernando Roberto de Andrade Lima, Whoody Alem Wanderley Araripe Farias, Victor Hugo Farias Ferreira da Silva, João Mário da Silva, Ferdinand de Jesus Lopes Filho, Jefferson Melo Gonçalves Pena, Larissa Cristina Silva dos Santos   +8 more
doaj   +1 more source

Covalently Linked Peptides and Membrane Potential Enable CyaA Segment Translocation

Advanced Science, EarlyView.
Using a newly developed Droplet Interface Bilayer‐Pipette assay, the authors show that two segments of the CyaA toxin cross membranes by distinct mechanisms. One segment translocates spontaneously, whereas the translocation of the other depends on membrane potential.
Gaia Scilironi, Nicolas Carvalho, Jacinthe Frangieh, Corentin Léger, Dorothée Raoux‐Barbot, J. Iñaki Guijarro, Daniel Ladant, Sophie Cribier, Nicolas Rodriguez, Alexandre Chenal   +9 more
wiley   +1 more source

A Lightweight File System Based Approach to Getting Data Ready for Data Management Solutions

Data Science Journal
According to the FAIR (findability, accessibility, interoperability, and reusability) principles, scientific data should always be stored with machine-readable descriptive metadata.
Albert K. Engstfeld, Johannes M. Hermann, Nicolas G. Hörmann, Julian Rüth   +3 more
doaj   +1 more source