Results 31 to 40 of about 36,600 (302)
Drug Import Replacement Is a Perspective Direction of the Development of Russian Economy
Управленческое консультирование, 2018 The development of the domestic pharmaceutical industry as a science-intensive and hightech sector of the country’s economy is, among other things, a pledge of the drug safety of the state, especially in the conditions of a modern complex political ...
K. D. Grigorieva
doaj +1 more source
, 2023 The goal of this paper is to present an approach to Hod Pair Capturing (HPC). $HPC$ is the most outstanding open problem of descriptive inner model theory. More specifically, we introduce two principles, the Direct Limit Independence and the Bounded Direct Limits, and show that they together imply HPC.
openaire +2 more sources
Reciprocal control of viral infection and phosphoinositide dynamics
FEBS Letters, EarlyView.Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
Médicaments génériques : pivot de la reconstruction de l’industrie pharmaceutique
Revue de la Régulation, 2015 The pharma has a particular significance given the challenges it involves for public health, economics, politics and ethics. The medicines production is therefore subject to multiple and complex regulations, both national and international. While some of
Philippe Abecassis, Nathalie Coutinet
doaj +1 more source
Journal of Family Medicine and Primary Care, 2020 Background: Generic drugs are low-cost alternatives to branded drugs. The government of India is encouraging physicians to prescribe the generics to decrease out-of-pocket expenditure of health care.
Jaykaran Charan +5 more
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FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
Frontiers in Pharmacology, 2014 Introduction: The appreciable growth in pharmaceutical expenditure has resulted in multiple initiatives across Europe to lower generic prices and enhance their utilisation. However, considerable variation in their use and prices.
Brian eGodman +30 more
doaj +1 more source
Non-equivalence of antibiotic generic drugs and risk for intensive care patients [PDF]
, 2013 Background: The underlying axiom in applying generic drugs is the equivalence of their active ingredient with the (usually more expensive) innovator product, an all-embracing statement with the insidious result that physicians assume that the generic ...
Barbeck, Mike +4 more
core
From Generation to Generation [PDF]
Clinical Chemistry, 2019 This work (Fig. 1) is a geometric abstraction that I created using pencil, ink, and acrylic paint on canvas. It could be interpreted as a spatial representation of time, peering along the branches of a pedigree or phylogenetic tree. The tree consists of three main branches with “cousins” on two of the branches connected by …
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Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source