Results 51 to 60 of about 513,714 (276)
Generic drugs: benefit/risk ratio
Неврология, нейропсихиатрия, психосоматика, 2021 The review discusses the interchangeability of medications, approaches to the registration of original and generic drugs, and types of their equivalence, as well as problems with generics in clinical practice.
E. A. Ushkalova +2 more
doaj +1 more source
Knowledge Completion for Generics using Guided Tensor Factorization [PDF]
Transactions of the Association for Computational Linguistics, 2016 Given a knowledge base or KB containing (noisy) facts about common nouns or generics, such as “all trees produce oxygen” or “some animals live in forests”, we consider the problem of inferring additional such facts at a precision similar to that of the ...
Hanie Sedghi, Ashish Sabharwal
semanticscholar +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Comprehensive bibliographic study of the framework of complex generic drugs
Journal of Taibah University Medical Sciencesالملخص: أهداف البحث: لوحظ مؤخرا نمو هائل في التحليل الببليوغرافي. ارتفع الطلب على الأدوية الجنيسة بشكل كبير على مدى العقود الثلاثة الماضية، ويبدو أن السوق مشبع.
Amatha Sreedevi, M.Pharm (Currently Ph.D Research Scholar) +2 more
doaj +1 more source
Management of Multiple Myeloma and Usage of Bortezomib: Perspective from India and Ukraine
Frontiers in Oncology, 2016 Novel treatment strategies have remarkably improved the multiple myeloma (MM) patients’ survival, with associated increased costs.A joint panel meet of international experts from India and Ukraine was held in New Delhi on 19th May 2016 focusing on: MM ...
India and Ukraine Haemato-oncology Group +12 more
doaj +1 more source
Technological forecasting & social change, 2019 Technology upgrading is a key element of industrialisation and catch-up in developing countries. It is understood that a successful technology upgrading is linked to a coupling of global knowledge flows with local technology effort. However, the changing
D. Kale
semanticscholar +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Generics and Context: Do Counterexamples Dissuade Acceptance of True Generic Statements?
Studies in Logic, Grammar and RhetoricThis study investigates whether the salience of counterexamples in discourse affects the acceptance of true generic statements. Building on previous theoretical and experimental work on generics, we examine whether generics are sensitive to contextual ...
Wajda Edyta, Karczewski Daniel
doaj +1 more source
The microbiome in human skin aging
FEBS Letters, EarlyView.Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana +3 more
wiley +1 more source
Mednarodno Inovativno Poslovanje, 2020 Declining productivity of pharmaceutical innovation resulted in an increased number of mergers & acquisitions in the pharmaceutical industry. Increased investments into research & development lack the resulting increases in patentable new ...
Davor Mance +2 more
doaj +1 more source