Results 51 to 60 of about 8,569 (263)
Imatinib Generics: Myths and Reality (Literature Review and Our Experience)
Клиническая онкогематология, 2014 The article describes the registration process of generic drugs in the Russian Federation. The article presents literature data and results of our own studies of the use of imatinib generics — PhilachromineÒ and GenfatinibÒ — in patients with chronic ...
K. M. Abdulkadyrov +2 more
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GENERALIZED SPACES OF GENERAL RELATIVITY [PDF]
Proceedings of the National Academy of Sciences, 1959 1. This paper is a revision of the paper with the same title which was published a year ago. The paper deals with a space of four dimensions V4 of coordinates xi as i takes the values 1 to 4. The geometry of the space is based upon the asymmetric functions gij and the asymmetric coefficients of connection Prk and upon the Einsteinm equation2 gij,k ...
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Discerning protein pools by selective staining with self‐labeling tags
FEBS Letters, EarlyView.Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley +1 more source
Analysis of the physicians’ perception of original and generic drugs in Poland
Arterial HypertensionBACKGROUND: Generic drugs play a crucial role in improving access to pharmacotherapy and reducing healthcare costs. However, physicians’ attitudes toward prescribing generics remain a key factor influencing their use in everyday clinical practice.
Marcin Lewandowski +10 more
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Dzheneriki pri lechenii ozhireniya
Ожирение и метаболизм, 2010 There are several pseudogenerics of Meridia® and Xenical®. Lindaxa®, registered in Russia, as a generic of Meridia®, can be at a disadvantage to a brand on cost-quality ratio.
doaj +1 more source
The microbiome in human skin aging
FEBS Letters, EarlyView.Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana +3 more
wiley +1 more source
PHARMACOECONOMIC ANALYSIS OF ANTIHYPERTENSIVE DRUG COMBINATIONS USE
Рациональная фармакотерапия в кардиологии, 2015 Aim. To pursue pharmacoeconomic analysis of two drug combinations of ACE inhibitor (enalapril) and diuretic.Material and methods. Patients with arterial hypertension degree 2 and diabetes mellitus type 2 without ischemic heart disease (n=56) were ...
E. I. Tarlovskaya +2 more
doaj +1 more source
Molecular Oncology, EarlyView.Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur +11 more
wiley +1 more source
Molecular Oncology, EarlyView.Interferon type 1 (IFN‐1) production and signaling is associated with the acquisition of therapy resistance, following chronic DNA damage, via Interferon‐related DNA damage resistance signature (IRDS) gene expression. An alternative, DNA damage‐independent role of sustained IFN‐1 mediated resistance was identified and characterized by the emergence of ...
Ashlyn Conant +11 more
wiley +1 more source
Generalizing generalized tries
Journal of Functional Programming, 2000 A trie is a search tree scheme that employs the structure of search keys to organize information. Tries were originally devised as a means to represent a collection of records indexed by strings over a fixed alphabet. Based on work by C. P. Wadsworth and others, R. H. Connelly and F. L.
openaire +2 more sources